SCHEMBL28439636

SCHEMBL28439636

CCCC(OCC1CO1)C(C)OCC1CO1

nearest known ligand 0.40

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
TDP1 Q9NUW8 1/20 0.38
TSHR P16473 2/20 0.33
MAPK1 P28482 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3458576 0.80 ALDH1A1 (0.46) ALDH1A1SMN1; SMN2TDP1TSHRMAPK1
SCHEMBL28450745 0.79 ALDH1A1 (0.36) ALDH1A1SMN1; SMN2TDP1TSHRMAPK1
SCHEMBL9918910 0.79 ALDH1A1 (0.53) ALDH1A1SMN1; SMN2TDP1TSHRMAPK1
SCHEMBL8628985 0.79 SMN1; SMN2 (0.44) ALDH1A1SMN1; SMN2TDP1TSHRMAPK1
Water SCHEMBL27971217 0.77 SMN1; SMN2 (0.42) ALDH1A1SMN1; SMN2TDP1TSHRMAPK1
SCHEMBL5045285 0.76 ALDH1A1 (0.50) ALDH1A1SMN1; SMN2TDP1TSHRMAPK1
SCHEMBL14893116 0.76 SMN1; SMN2 (0.45) ALDH1A1SMN1; SMN2TDP1TSHRMAPK1
SCHEMBL18111 0.76 SMN1; SMN2 (0.45) ALDH1A1SMN1; SMN2TDP1TSHRMAPK1
SCHEMBL17559523 0.76 ALDH1A1 (0.43) ALDH1A1SMN1; SMN2TDP1TSHRMAPK1
SCHEMBL21795689 0.76 ALDH1A1 (0.43) ALDH1A1SMN1; SMN2TDP1TSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111491976-B New use of isosorbide 艾伦塔斯欧洲有限公司 2023-03-24 CN disclosed
CN-111491976-A New use of isosorbide 艾伦塔斯欧洲有限公司 2020-08-04 CN disclosed