Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6859067 | 0.90 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2TDP1TSHRMAPK1 | |
| SCHEMBL14696629 | 0.87 | TSHR (0.48) | ALDH1A1SMN1; SMN2TDP1TSHRMAPK1 | |
| SCHEMBL6306013 | 0.85 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2TDP1TSHRMAPK1 | |
| SCHEMBL6305973 | 0.81 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2TDP1TSHRMAPK1 | |
| SCHEMBL13818304 | 0.80 | TSHR (0.50) | ALDH1A1SMN1; SMN2TDP1TSHRMAPK1 | |
| SCHEMBL4471116 | 0.80 | TSHR (0.50) | ALDH1A1SMN1; SMN2TDP1TSHRMAPK1 | |
| SCHEMBL729850 | 0.80 | TSHR (0.50) | ALDH1A1SMN1; SMN2TDP1TSHRMAPK1 | |
| SCHEMBL10155854 | 0.80 | TSHR (0.50) | ALDH1A1SMN1; SMN2TDP1TSHRMAPK1 | |
| SCHEMBL28439636 | 0.79 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2TDP1TSHRMAPK1 | |
| SCHEMBL21723666 | 0.79 | TSHR (0.41) | ALDH1A1SMN1; SMN2TDP1TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170022223-A1 | METHOD FOR PRODUCING SURFACE-MODIFIED BASE MATERIAL, METHOD FOR PRODUCING JOINED BODY, NEW HYDROSILANE COMPOUND, SURFACE TREATMENT AGENT, SURFACE TREATMENT AGENT KIT, AND SURFACE-MODIFIED BASE MATERIAL | SIHS REACT CO., LTD. (JP) | 2017-01-26 | — | — | US | disclosed |
| US-9000110-B2 | Fluoroalkyl group-containing n-substituted (meth)acrylamide compound, polymer thereof, and use thereof | AGC SEIMI CHEMICAL CO., LTD. (JP) | 2015-04-07 | — | — | US | disclosed |
| US-20120149860-A1 | FLUOROALKYL GROUP-CONTAINING N-SUBSTITUTED (METH)ACRYLAMIDE COMPOUND, POLYMER THEREOF , AND USE THEREOF | AGC SEIMI CHEMICAL CO.,LTD. (JP) | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170022223-A1 | METHOD FOR PRODUCING SURFACE-MODIFIED BASE MATERIAL, METHOD FOR PRODUCING JOINED BODY, NEW HYDROSILANE COMPOUND, SURFACE TREATMENT AGENT, SURFACE TREATMENT AGENT KIT, AND SURFACE-MODIFIED BASE MATERIAL | BRSK1, SIK2, KIT | ALDH1A1 2395/4885SMN1; SMN2 1743/4885TDP1 2309/4885 |
| US-20120149860-A1 | FLUOROALKYL GROUP-CONTAINING N-SUBSTITUTED (METH)ACRYLAMIDE COMPOUND, POLYMER THEREOF , AND USE THEREOF | AFF2, AFF1, FRG1 | ALDH1A1 3201/4885SMN1; SMN2 3754/4885TDP1 2632/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.