Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | LPO | P22079 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | MITF | O75030 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14975141 | 0.82 | LMNA (0.53) | BCHELMNATSHRALDH1A1KDM4E | |
| SCHEMBL16058318 | 0.82 | LMNA (0.53) | BCHELMNATSHRALDH1A1KDM4E | |
| SCHEMBL16058688 | 0.82 | MAPT (0.41) | TSHRALDH1A1GAAL3MBTL1MAPK1 | |
| SCHEMBL16058385 | 0.82 | P2RX4 (0.52) | LMNAALDH1A1KDM4EGAAL3MBTL1 | |
| SCHEMBL16057185 | 0.82 | LMNA (0.53) | BCHELMNATSHRALDH1A1KDM4E | |
| SCHEMBL14977311 | 0.82 | LMNA (0.53) | BCHELMNATSHRALDH1A1KDM4E | |
| SCHEMBL16058203 | 0.82 | LMNA (0.53) | BCHELMNATSHRALDH1A1KDM4E | |
| SCHEMBL16057307 | 0.80 | NAAA (0.41) | LMNATSHRALDH1A1KDM4EGAA | |
| Hydrochloric Acid SCHEMBL5450987 | 0.79 | BCHE (0.45) | BCHELPOLMNACYP1A2TSHR | |
| SCHEMBL16057948 | 0.78 | P2RX4 (0.50) | LMNATSHRALDH1A1L3MBTL1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107001273-B | Pyridine derivatives | 安斯泰来制药株式会社 | 2020-05-12 | — | — | CN | disclosed |