Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | GABRP | O00591 | 2/20 | 0.50 |
| ▸ | GABRD | O14764 | 2/20 | 0.50 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.50 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.50 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.50 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.50 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.50 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.50 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.50 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.50 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.50 |
| ▸ | GABRE | P78334 | 2/20 | 0.50 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.50 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.50 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.50 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL756717 | 0.98 | — | — | |
| SCHEMBL52133 | 0.98 | — | — | |
| Hydrochloric Acid SCHEMBL21820004 | 0.95 | CYP2D6 (0.61) | CYP2D6NFKB1LMNAMAPTGABRP | |
| Glutamic Acid SCHEMBL7821241 | 0.87 | GRM8 (0.72) | CYP2D6NFKB1LMNAMAPTGABRP | |
| Alanine SCHEMBL29050844 | 0.87 | GABRP (0.54) | CYP2D6NFKB1LMNAMAPTGABRP | |
| Aspartic Acid SCHEMBL7823074 | 0.84 | GRM8 (0.55) | CYP2D6NFKB1LMNAMAPTGABRP | |
| SCHEMBL10530673 | 0.84 | ENPEP (0.52) | CYP2D6NFKB1LMNAMAPTGABRP | |
| SCHEMBL11453652 | 0.84 | ENPEP (0.52) | CYP2D6NFKB1LMNAMAPTGABRP | |
| SCHEMBL887143 | 0.78 | — | — | |
| SCHEMBL61064 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111587114-A | Use of imidazopyrimidines for modulating the immune response in humans | 儿童医学中心公司 | 2020-08-25 | — | — | CN | disclosed |