Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.49 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SCN7A | Q01118 | 2/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.44 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.44 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31103273 | 0.84 | MAPT (0.42) | SMN1; SMN2MEN1MAPTHTTKMT2A | |
| SCHEMBL5714487 | 0.83 | KMT2A (0.58) | SMN1; SMN2MEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL5715592 | 0.82 | TRPA1 (0.47) | SMN1; SMN2MEN1KMT2ATRPA1ALDH1A1 | |
| SCHEMBL5714708 | 0.81 | TP53 (0.55) | — | |
| SCHEMBL5714464 | 0.81 | PANK3 (0.46) | HRH3MEN1KMT2ATRPA1TRPV1 | |
| SCHEMBL5714455 | 0.81 | CYP3A4 (0.46) | SMN1; SMN2MAPTABL1SRCALDH1A1 | |
| SCHEMBL5714890 | 0.81 | ALDH1A1 (0.55) | MEN1MAPTKMT2AALDH1A1TSHR | |
| SCHEMBL5714914 | 0.80 | TP53 (0.43) | SMN1; SMN2MAPTABL1SRCTSHR | |
| SCHEMBL5714918 | 0.80 | TP53 (0.45) | MAPTTRPA1ALDH1A1 | |
| SCHEMBL5715532 | 0.80 | TP53 (0.48) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111511361-A | Aminocarbonate and urea compounds as multikinase inhibitors | 安杰斯制药公司 | 2020-08-07 | — | — | CN | disclosed |