SCHEMBL28440

SCHEMBL28440

O=[C]OC(Br)(Br)CBr

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1336710 0.69
SCHEMBL2109341 0.67
SCHEMBL4037011 0.63
SCHEMBL11543944 0.59 ALDH1A1 (0.32)
SCHEMBL9246320 0.58
SCHEMBL2110285 0.57
SCHEMBL9721122 0.56 ALDH1A1 (0.35)
SCHEMBL8751772 0.56
SCHEMBL2109191 0.56
SCHEMBL2109307 0.56

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 452 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1514542-B1 Medicinal composition comprising Tacrine or Donepezil for improving brain function. TOYAMA CHEMICAL CO LTD (JP) 2012-02-22 EP claimed
US-4461906-A IMPROVING INTELLECTUAL CAPACITY HOFFMANN-LA ROCHE INC. (US) 1984-07-24 US claimed
US-4452807-A CENTRAL NERVOUS SYSTEM DISORDERS HOFFMANN-LA ROCHE INC. (US) 1984-06-05 US claimed
US-4269773-A CEPHALOSPORINS SHIONOGI & CO., LTD. (JP) 1981-05-26 US claimed
US-4267340-A BACTERICIDES; SYNTHESIS OF PENICILLINS AND CEPHALOSPORINS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1981-05-12 US claimed
US-4097665-A Diacylnucleosides and process for preparing the same ASAHI KASEI KOGYO KABUSHIKI KAISHA (JA) 1978-06-27 US claimed
US-4009159-A PENICILLINS FUJISAWA PHARMACEUTICAL CO., LTD. (JA) 1977-02-22 US claimed
US-3993646-A Process for the ring expansion of penicillins to cephalosporin compounds FUJISAWA PHARMACEUTICAL CO., LTD. (JA) 1976-11-23 US claimed
CN-118284608-A Compounds as BCL-2 inhibitors 重庆复创医药研究有限公司 2024-07-02 CN disclosed
CN-118215661-A Compounds as BCL-2 inhibitors 重庆复创医药研究有限公司 2024-06-18 CN disclosed
EP-4119560-B1 APOPTOSIS-INDUCING AGENTS FOCHON PHARMACEUTICALS LTD (CN) 2024-06-05 EP disclosed
EP-3768661-B1 DEUTERATED COMPOUNDS AS ROCK INHIBITORS FOCHON PHARMACEUTICALS LTD (CN) 2024-05-01 EP disclosed
EP-3565815-B1 COMPOUNDS AS BCL-2-SELECTIVE APOPTOSIS-INDUCING AGENTS FOCHON PHARMACEUTICALS LTD (CN) 2024-03-13 EP disclosed
CN-114127078-B Heterocompounds and methods of use thereof 重庆复创医药研究有限公司 2024-03-01 CN disclosed
US-4071527-A Certain benzothiazole compounds FUJISAWA PHARMACEUTICAL CO., LTD. (JA) 1978-01-31 US disclosed
US-4049664-A ANTIALLERGENS, ANTIASTHMATICS FUJISAWA PHARMACEUTICAL CO., LTD. (JA) 1977-09-20 US disclosed
US-4036847-A ANTIBACTERIAL FUJISAWA PHARMACEUTICAL CO., LTD. (JA) 1977-07-19 US disclosed
US-4009159-A PENICILLINS FUJISAWA PHARMACEUTICAL CO., LTD. (JA) 1977-02-22 US disclosed
US-3993646-A Process for the ring expansion of penicillins to cephalosporin compounds FUJISAWA PHARMACEUTICAL CO., LTD. (JA) 1976-11-23 US disclosed
US-3965122-A ANTIALLERGENS FUJISAWA PHARMACEUTICAL CO., LTD. (JA) 1976-06-22 US disclosed