Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.50 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 7/20 | 0.48 |
| ▸ | MEN1 | O00255 | 7/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | CASR | P41180 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12332820 | 0.85 | CYP4F2 (0.58) | CYP4F2CYP4A11ALDH1A1TSHRLMNA | |
| SCHEMBL7153424 | 0.85 | ALDH1A1 (0.51) | ALDH1A1TSHRLMNAMEN1KMT2A | |
| SCHEMBL30750476 | 0.82 | CYP4F2 (0.72) | CYP4F2CYP4A11ALDH1A1TSHRLMNA | |
| SCHEMBL14817015 | 0.82 | LOXL2 (0.54) | CYP4F2CYP4A11ALDH1A1TSHRLMNA | |
| SCHEMBL13066708 | 0.82 | CYP4F2 (0.51) | CYP4F2CYP4A11ALDH1A1TSHRLMNA | |
| SCHEMBL844331 | 0.82 | CYP4F2 (0.72) | CYP4F2CYP4A11ALDH1A1TSHRLMNA | |
| SCHEMBL7150326 | 0.82 | CA12 (0.59) | ALDH1A1TSHRLMNASMN1; SMN2HPGD | |
| SCHEMBL31343271 | 0.82 | LOXL2 (0.54) | CYP4F2CYP4A11ALDH1A1TSHRLMNA | |
| Hydrochloric Acid SCHEMBL30933600 | 0.81 | LOXL2 (0.53) | CYP4F2CYP4A11ALDH1A1TSHRLMNA | |
| Hydrochloric Acid SCHEMBL9931554 | 0.81 | LOXL2 (0.53) | CYP4F2CYP4A11ALDH1A1TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108997325-B | Aryl bithiazole compound and application thereof | 浙江工业大学 | 2020-08-04 | — | — | CN | disclosed |