Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 2/20 | 0.38 |
| ▸ | GSK3A | P49840 | 2/20 | 0.38 |
| ▸ | GSK3B | P49841 | 2/20 | 0.38 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.38 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.38 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.38 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | CSNK1G3 | Q9Y6M4 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | TOP2A | P11388 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9014024 | 0.77 | PRKD3 (0.40) | PIM1GSK3AGSK3BPIM3PRKD3 | |
| SCHEMBL29023850 | 0.76 | KDM4E (0.41) | PIM1GSK3AGSK3BPIM3PRKD3 | |
| SCHEMBL9715578 | 0.68 | KDM4E (0.39) | PIM1GSK3AGSK3BPIM3PRKD3 | |
| SCHEMBL9216084 | 0.68 | KMT2A (0.45) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL10574880 | 0.67 | KDM4E (0.41) | PIM1GSK3AGSK3BPIM3PRKD3 | |
| SCHEMBL3004295 | 0.67 | LMNA (0.56) | PIM1GSK3AGSK3BPIM3PRKD3 | |
| SCHEMBL10976694 | 0.67 | ALDH1A1 (0.36) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL9457406 | 0.67 | PRKD3 (0.47) | PIM1GSK3AGSK3BPIM3PRKD3 | |
| SCHEMBL5908346 | 0.67 | KMT2A (0.43) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL8540093 | 0.67 | KCNH2 (0.41) | PIM1GSK3AGSK3BPIM3PRKD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111320581-A | Synthesis method of quinoline carboxylic ester | 山东省联合农药工业有限公司 | 2020-06-23 | — | — | CN | disclosed |