SCHEMBL28440280

SCHEMBL28440280

CC(C(N)=O)C(=O)Oc1ccc([N+](=O)[O-])cc1

nearest known ligand 0.54

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.54
BCL9 O00512 1/20 0.51
CTNNB1 P35222 1/20 0.51
HTR2A P28223 1/20 0.51
KMT2A Q03164 5/20 0.50
PKM P14618 1/20 0.50
HGFAC Q04756 1/20 0.48
ALDH1A1 P00352 2/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
TSHR P16473 1/20 0.46
MGLL Q99685 2/20 0.46
MEN1 O00255 2/20 0.45
MAPT P10636 2/20 0.45
NPC1 O15118 1/20 0.45
HTT P42858 1/20 0.45
RAB9A P51151 1/20 0.45
CRHBP P24387 1/20 0.43
CRHR2 Q13324 1/20 0.43
LMNA P02545 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9435291 0.84 GAA (0.57) GAABCL9CTNNB1HTR2AKMT2A
SCHEMBL515913 0.84 GAA (0.57) GAABCL9CTNNB1HTR2AKMT2A
SCHEMBL4683792 0.83 GAA (0.60) GAABCL9CTNNB1HTR2AKMT2A
Water SCHEMBL4754930 0.83 GAA (0.55) GAABCL9CTNNB1HTR2AKMT2A
SCHEMBL14307582 0.82 GAA (0.58) GAABCL9CTNNB1HTR2AKMT2A
SCHEMBL4752026 0.82 GAA (0.58) GAABCL9CTNNB1HTR2AKMT2A
SCHEMBL7613846 0.81 GAA (0.54) GAABCL9CTNNB1HTR2AKMT2A
SCHEMBL4805620 0.81 GAA (0.54) GAABCL9CTNNB1HTR2AKMT2A
SCHEMBL16671852 0.81 GAA (0.57) GAABCL9CTNNB1HTR2AKMT2A
SCHEMBL18285287 0.81 GAA (0.57) GAABCL9CTNNB1HTR2AKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108060186-B Biological preparation method of p-nitrobenzyl alcohol malonic acid monoester 台州学院 2020-08-28 CN disclosed