Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | BCL9 | O00512 | 1/20 | 0.51 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MGLL | Q99685 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4805620 | 1.00 | GAA (0.54) | GAABCL9CTNNB1HTR2AKMT2A | |
| SCHEMBL9435291 | 0.87 | GAA (0.57) | GAABCL9CTNNB1HTR2AKMT2A | |
| SCHEMBL515913 | 0.87 | GAA (0.57) | GAABCL9CTNNB1HTR2AKMT2A | |
| Water SCHEMBL4754930 | 0.86 | GAA (0.55) | GAABCL9CTNNB1HTR2AKMT2A | |
| SCHEMBL4683792 | 0.83 | GAA (0.60) | GAABCL9CTNNB1HTR2AKMT2A | |
| SCHEMBL29488801 | 0.83 | GAA (0.49) | GAABCL9CTNNB1HTR2AKMT2A | |
| SCHEMBL4752026 | 0.82 | GAA (0.58) | GAABCL9CTNNB1HTR2AKMT2A | |
| SCHEMBL14307582 | 0.82 | GAA (0.58) | GAABCL9CTNNB1HTR2AKMT2A | |
| SCHEMBL11478677 | 0.81 | GAA (0.54) | GAABCL9CTNNB1HTR2AKMT2A | |
| SCHEMBL28440280 | 0.81 | GAA (0.54) | GAABCL9CTNNB1HTR2AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250352516-A1 | ISOTOPE-ENRICHED 3-AMINO-1-PROPANESULFONIC ACID DERIVATIVES FOR THE TREATMENT OF CEREBROVASCULAR DISEASE | RISEN SUZHOU PHARMA TECH CO LTD (CN) | 2025-11-20 | — | — | US | disclosed |
| CN-116059192-B | Use of isotopically enriched 3-amino-1-propanesulfonic acid and derivatives thereof | 润佳（苏州）医药科技有限公司 | 2024-10-29 | — | — | CN | disclosed |
| CN-114805211-B | Isotopically enriched 3-amino-1-propanesulfonic acid derivatives, pharmaceutical compositions and uses thereof | 润佳（苏州）医药科技有限公司 | 2024-08-23 | — | — | CN | disclosed |
| CN-112791078-B | Use of isotopically enriched 3-amino-1-propanesulfonic acid and derivatives thereof | 润佳（苏州）医药科技有限公司 | 2022-12-06 | — | — | CN | disclosed |
| CN-114805211-A | Isotopically enriched 3-amino-1-propanesulfonic acid derivatives, pharmaceutical compositions and uses thereof | 润佳（苏州）医药科技有限公司 | 2022-07-29 | — | — | CN | disclosed |
| EP-1173413-A1 | USE OF 2,4-DIAMINO-3-HYDROXYCARBOXYLIC ACID DERIVATIVES AS PROTEASOME INHIBITORS | Novartis AG (CH) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000064863-A1 | USE OF 2,4-DIAMINO-3-HYDROXYCARBOXYLIC ACID DERIVATIVES AS PROTEASOME INHIBITORS | NOVARTIS AG (CH) | 2000-11-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250352516-A1 | ISOTOPE-ENRICHED 3-AMINO-1-PROPANESULFONIC ACID DERIVATIVES FOR THE TREATMENT OF CEREBROVASCULAR DISEASE | SLC7A1, SLC1A1, SLC1A3 | GAA 160/4885BCL9 4276/4885CTNNB1 1708/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.