SCHEMBL28440346

SCHEMBL28440346

CCC(=O)C1CCC(=O)CC1

nearest known ligand 0.50

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 1/20 0.32
GHSR Q92847 1/20 0.32
RAB9A P51151 2/20 0.32
TLR4 O00206 4/20 0.31
SPR P35270 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19526243 0.87 PARP1 (0.35) GHSR
SCHEMBL22281750 0.87 PARP1 (0.35) GHSR
SCHEMBL256670 0.83
SCHEMBL10253143 0.80 ESR2 (0.31) ESR2
SCHEMBL17733935 0.79 ABL1 (0.48) TLR4
SCHEMBL14196482 0.78 USP2 (0.43) RAB9A
SCHEMBL16359540 0.77 ALDH1A1 (0.31)
SCHEMBL15125170 0.76
SCHEMBL256032 0.75
SCHEMBL27787478 0.75 TDP1 (0.33) TLR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109232471-B Preparation method of pramipexole dihydrochloride 安徽省庆云医药股份有限公司 2022-05-10 CN disclosed
CN-106905286-B Flavonoid compound derivative and application thereof 江苏恩华药业股份有限公司 2020-07-24 CN disclosed