Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL256670 | 0.78 | — | — | |
| SCHEMBL15116626 | 0.77 | LMNA (0.35) | — | |
| SCHEMBL28440346 | 0.77 | ESR2 (0.32) | — | |
| SCHEMBL15105594 | 0.76 | MAPT (0.46) | ALDH1A1MAPTTDP1 | |
| SCHEMBL10253143 | 0.75 | ESR2 (0.31) | — | |
| SCHEMBL849145 | 0.74 | GABRP (0.41) | ALDH1A1POLBMAPTTDP1 | |
| SCHEMBL15113761 | 0.72 | — | — | |
| SCHEMBL256032 | 0.71 | — | — | |
| SCHEMBL27787478 | 0.71 | TDP1 (0.33) | ALDH1A1MAPTTDP1 | |
| SCHEMBL2128026 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015005901-A1 | COMBINATIONS OF HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2015-01-15 | — | — | WO | disclosed |
| WO-2013106520-A1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2013-07-18 | — | — | WO | disclosed |