SCHEMBL28440496

SCHEMBL28440496

N#CC(=Cc1ccccc1Br)C(N)=O

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 2/20 0.60
KDM4E B2RXH2 6/20 0.57
CYP1A2 P05177 3/20 0.57
MEN1 O00255 3/20 0.57
KMT2A Q03164 3/20 0.57
CYP2C9 P11712 2/20 0.57
POLB P06746 2/20 0.54
EGFR P00533 4/20 0.53
GAA P10253 3/20 0.53
LMNA P02545 2/20 0.53
LCK P06239 2/20 0.53
GPR55 Q9Y2T6 1/20 0.48
CYP3A4 P08684 1/20 0.47
MAPT P10636 4/20 0.46
TDP1 Q9NUW8 2/20 0.46
ALDH1A1 P00352 1/20 0.46
ERBB2 P04626 1/20 0.46
TP53 P04637 1/20 0.46
HPGD P15428 1/20 0.46
HSD17B10 Q99714 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28439082 0.80 KDM4E (0.61) MCL1KDM4ECYP1A2MEN1KMT2A
SCHEMBL28897442 0.80 MCL1 (0.60) MCL1KDM4ECYP1A2MEN1KMT2A
SCHEMBL28436909 0.80 MCL1 (0.60) MCL1KDM4ECYP1A2MEN1KMT2A
SCHEMBL21457377 0.80 POLB (0.64) KDM4ECYP1A2MEN1KMT2ACYP2C9
SCHEMBL21457375 0.80 POLB (0.64) KDM4ECYP1A2MEN1KMT2ACYP2C9
SCHEMBL9027589 0.78 MCL1 (0.57) MCL1KDM4ECYP1A2MEN1KMT2A
SCHEMBL28450866 0.76 LMNA (0.60) MCL1KDM4ECYP1A2MEN1KMT2A
SCHEMBL28436908 0.76 KDM4E (0.76) MCL1KDM4ECYP1A2MEN1KMT2A
SCHEMBL21457421 0.76 ALDH1A1 (0.60) KDM4ECYP1A2MEN1KMT2ACYP2C9
SCHEMBL21457419 0.76 ALDH1A1 (0.60) KDM4ECYP1A2MEN1KMT2ACYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111499554-B Phenyl pyrrole compound and application of bactericidal activity thereof 黑龙江大学 2023-06-23 CN disclosed
CN-111393348-B Nitrogen-substituted phenylpyrrole compound and application thereof in plant sterilization 黑龙江大学 2023-03-28 CN disclosed
CN-111499554-A Phenyl pyrrole compound and application of bactericidal activity thereof 黑龙江大学 2020-08-07 CN disclosed
CN-111393348-A Nitrogen-substituted phenylpyrrole compound and application thereof in plant sterilization 黑龙江大学 2020-07-10 CN disclosed