Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21751870 | 0.99 | DGAT1 (0.34) | DGAT1CYP2C9TSHR | |
| SCHEMBL20767572 | 0.86 | DGAT1 (0.35) | DGAT1 | |
| SCHEMBL25615934 | 0.83 | DGAT1 (0.37) | DGAT1 | |
| SCHEMBL25349464 | 0.81 | DGAT1 (0.38) | DGAT1 | |
| SCHEMBL21751788 | 0.81 | DGAT1 (0.36) | DGAT1 | |
| SCHEMBL21751562 | 0.80 | DGAT1 (0.38) | DGAT1 | |
| SCHEMBL20553711 | 0.80 | DGAT1 (0.37) | DGAT1 | |
| SCHEMBL31609983 | 0.80 | — | — | |
| Ammonia Solution, Strong SCHEMBL28939497 | 0.79 | DGAT1 (0.38) | DGAT1 | |
| SCHEMBL25886857 | 0.79 | DGAT1 (0.38) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111448198-A | Condensed heterocyclic derivatives as Bcl-2 inhibitors for the treatment of neonatal diseases | 新波制药有限公司 | 2020-07-24 | — | — | CN | disclosed |