Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21751870 | 0.87 | DGAT1 (0.34) | DGAT1 | |
| SCHEMBL28440805 | 0.86 | DGAT1 (0.33) | DGAT1 | |
| SCHEMBL25349464 | 0.84 | DGAT1 (0.38) | DGAT1 | |
| SCHEMBL21751562 | 0.84 | DGAT1 (0.38) | DGAT1 | |
| SCHEMBL26195129 | 0.83 | DGAT1 (0.34) | DGAT1 | |
| Ammonia Solution, Strong SCHEMBL28939497 | 0.83 | DGAT1 (0.38) | DGAT1 | |
| SCHEMBL25886857 | 0.83 | DGAT1 (0.38) | DGAT1 | |
| SCHEMBL21751919 | 0.82 | DGAT1 (0.34) | DGAT1 | |
| SCHEMBL23165244 | 0.82 | DGAT1 (0.37) | DGAT1 | |
| SCHEMBL21751778 | 0.82 | DGAT1 (0.37) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3672975-A1 | CONDENSED HETEROCYCLIC DERIVATIVES AS BCL-2 INHIBITORS FOR THE TREATMENT OF NEOPLASTIC DISEASES | Newave Pharmaceutical Inc. (US) | 2020-07-01 | — | — | EP | disclosed |
| WO-2020041406-A1 | BCL-2 INHIBITORS | NEWAVE PHARMACEUTICAL INC. (US) | 2020-02-27 | — | — | WO | disclosed |
| WO-2019040550-A1 | CONDENSED HETEROCYCLIC DERIVATIVES AS BCL-2 INHIBITORS FOR THE TREATMENT OF NEOPLASTIC DISEASES | NEWAVE PHARMACEUTICAL INC. (US) | 2019-02-28 | — | — | WO | disclosed |