SCHEMBL284409

SCHEMBL284409

Cc1ccc(-c2ccc(C)cc2C)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 2/20 0.47
ESR1 P03372 1/20 0.47
GAA P10253 1/20 0.45
MAPT P10636 1/20 0.45
TDP1 Q9NUW8 3/20 0.44
TP53 P04637 1/20 0.44
HSD17B1 P14061 1/20 0.42
ACHE P22303 1/20 0.42
MAOB P27338 2/20 0.41
ADORA3 P0DMS8 1/20 0.41
MEN1 O00255 2/20 0.41
NPC1 O15118 2/20 0.41
RAB9A P51151 2/20 0.41
KMT2A Q03164 2/20 0.41
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
MAOA P21397 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP2A6 P11509 1/20 0.39
ALDH1A1 P00352 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18722306 0.97 ESR2 (0.45) ESR2ESR1GAAMAPTTDP1
SCHEMBL22111431 0.87 ESR2 (0.43) ESR2ESR1TDP1HSD17B1ACHE
SCHEMBL19618901 0.87 ESR2 (0.43) ESR2ESR1TDP1HSD17B1ACHE
SCHEMBL15026010 0.87 NPC1 (0.49) ESR2ESR1GAAMAPTTDP1
SCHEMBL11966921 0.87 ESR2 (0.39) ESR2ESR1GAAMAPTTDP1
SCHEMBL1513689 0.86 ESR2 (0.60) ESR2ESR1TDP1TP53HSD17B1
SCHEMBL5597351 0.86 ACHE (0.50) ESR2ESR1GAAMAPTTDP1
SCHEMBL29565280 0.86 ACHE (0.50) ESR2ESR1GAAMAPTTDP1
SCHEMBL14850871 0.86 KMT2A (0.46) ESR2ESR1GAAMAPTMEN1
SCHEMBL26463820 0.86 MAPT (0.44) ESR2ESR1GAAMAPTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1028516-C Composition based of methylating and benzylating derivatives of diphenylmethane and application as dielectric ATOCHEM (FR) 1995-05-24 CN claimed
CN-1054415-A With ditan methylate and the benzyl derivative is the composition of main component and as dielectric application ATOCHEM (FR) 1991-09-11 CN claimed
EP-3883522-B1 USE OF A POLYETHER-MODIFIED POLYDIMETHYL SILOXANE FOR REDUCING THE STICKINESS OF A DENTAL IMPRESSION COMPOSITION SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2025-01-08 EP disclosed
US-11872292-B2 Cationically and radiation curable composition 3M INNOVATIVE PROPERTIES COMPANY (US) 2024-01-16 US disclosed
WO-2022186150-A1 CORE-SHEATH COMPOSITE FIBER, PRODUCTION METHOD THEREFOR, AND FIBER STRUCTURE 株式会社クラレ 2022-09-09 WO disclosed
EP-3319580-B1 KIT OF PARTS CONTAINING A CATIONICALLY HARDENABLE COMPOSITION AND USE AS DENTAL RETRACTION MATERIAL 3M INNOVATIVE PROPERTIES CO (US) 2022-04-06 EP disclosed
EP-3515396-B1 CATIONICALLY AND RADIATION CURABLE COMPOSITION 3M INNOVATIVE PROPERTIES CO (US) 2022-01-05 EP disclosed
EP-3883522-A1 CURABLE COMPOSITION CONTAINING A POLYETHER-MODIFIED POLYDIMETHYL SILOXANE 3M Innovative Properties Company (US) 2021-09-29 EP disclosed
US-10952933-B2 Kit of parts containing a cationically hardenable composition and use as dental retraction material 3M INNOVATIVE PROPERTIES COMPANY (US) 2021-03-23 US disclosed
EP-2459151-B1 CATIONICALLY HARDENABLE DENTAL COMPOSITION, PROCESS OF PRODUCTION AND USE THEREOF 3M INNOVATIVE PROPERTIES CO (US) 2021-03-03 EP disclosed
US-20200390778-A1 COMPOUNDS AND METHODS FOR TREATING OXALATE-RELATED DISEASES OXALURX, INC. 2020-12-17 US disclosed
EP-0980410-A1 THERMAL FLUID BLENDS CONTAINING 1,2,3,4-TETRAHYDRO(1-PHENYLETHYL)NAPHTHALENE THE DOW CHEMICAL COMPANY (US) 2000-02-23 EP disclosed
WO-1998050483-A1 THERMAL FLUID BLENDS CONTAINING 1,2,3,4-TETRAHYDRO(1-PHENYLETHYL)NAPHTHALENE THE DOW CHEMICAL COMPANY (US) 1998-11-12 WO disclosed
CN-1028516-C Composition based of methylating and benzylating derivatives of diphenylmethane and application as dielectric ATOCHEM (FR) 1995-05-24 CN disclosed
CN-1018732-B POLYARYLALKANE OLIGOMER COMPOSITIONS AND PROCESS FOR THEIR MANUFACTURE ATOCHEM (FR) 1992-10-21 CN disclosed
CN-1016334-B Process for the production of polyarylalkane oligomers containing xylene units ATOCHEM (FR) 1992-04-22 CN disclosed
CN-1054415-A With ditan methylate and the benzyl derivative is the composition of main component and as dielectric application ATOCHEM (FR) 1991-09-11 CN disclosed
CN-1054415-A With ditan methylate and the benzyl derivative is the composition of main component and as dielectric application ATOCHEM (FR) 1991-09-11 CN disclosed
CN-1031365-A The composition of multiple aromatic yl alkane oligomer and its production method ATOCHEM (FR) 1989-03-01 CN disclosed
CN-1031219-A Contain the composition of multiple aromatic yl alkane oligomer of xylene chain link and its production method ATOCHEM (FR) 1989-02-22 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10952933-B2 Kit of parts containing a cationically hardenable composition and use as dental retraction material SET, SETDB1, DNMT3A ESR2 3821/4885ESR1 4014/4885GAA 2715/4885
US-11872292-B2 Cationically and radiation curable composition RAD51, SMARCA1, SMARCA4 ESR2 2547/4885ESR1 2273/4885GAA 2560/4885
US-20200390778-A1 COMPOUNDS AND METHODS FOR TREATING OXALATE-RELATED DISEASES XDH, PNPO, LOX ESR2 4344/4885ESR1 4780/4885GAA 12/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.