Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9842935 | 0.86 | TP53 (0.66) | MAPTGAASMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL13989319 | 0.84 | GAA (0.73) | MAPTGAAATMSMN1; SMN2RAB9A | |
| SCHEMBL9429120 | 0.84 | TSHR (0.66) | MAPTGAASMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL104611 | 0.83 | SMN1; SMN2 (0.67) | MAPTGAAATMSMN1; SMN2RAB9A | |
| SCHEMBL28897295 | 0.80 | MAPT (0.64) | MAPTGAAATMSMN1; SMN2RAB9A | |
| SCHEMBL14147697 | 0.80 | CA12 (0.56) | MAPTGAAATMSMN1; SMN2RAB9A | |
| SCHEMBL14237971 | 0.80 | TSHR (0.76) | MAPTGAAATMSMN1; SMN2RAB9A | |
| SCHEMBL11161353 | 0.80 | MAPT (0.50) | MAPTGAAATMSMN1; SMN2RAB9A | |
| SCHEMBL15981124 | 0.79 | SMN1; SMN2 (0.59) | MAPTGAASMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL4790863 | 0.79 | ALDH1A1 (0.65) | MAPTGAAATMSMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111574322-A | Preparation method of difluoromethyl aromatic compound | 南京工业大学 | 2020-08-25 | — | — | CN | disclosed |