Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 13/20 | 0.69 |
| ▸ | CNR1 | P21554 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.47 |
| ▸ | FAAH | O00519 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28445018 | 0.81 | CNR2 (1.00) | CNR2CNR1TSHRKDM4EALDH1A1 | |
| SCHEMBL28305040 | 0.80 | CNR2 (1.00) | CNR2CNR1TSHRKDM4EALDH1A1 | |
| SCHEMBL16764992 | 0.77 | CNR2 (0.60) | CNR2CNR1TSHRKDM4EALDH1A1 | |
| SCHEMBL28444022 | 0.76 | CNR2 (0.70) | CNR2CNR1TSHRKDM4EALDH1A1 | |
| SCHEMBL28435121 | 0.73 | CNR2 (1.00) | CNR2CNR1TSHREPHX2FAAH | |
| SCHEMBL24131114 | 0.72 | ALDH1A1 (0.57) | CNR2CNR1KDM4EALDH1A1HPGD | |
| SCHEMBL2816680 | 0.71 | TET2 (0.51) | TSHRKDM4EALDH1A1MAPTALOX12 | |
| SCHEMBL29600892 | 0.71 | TET2 (0.51) | TSHRKDM4EALDH1A1MAPTALOX12 | |
| SCHEMBL16539027 | 0.71 | IRAK4 (0.46) | CNR2CNR1KDM4EALDH1A1RAB9A | |
| SCHEMBL2638308 | 0.71 | PABPC1 (0.65) | CNR2TSHRKDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111518095-A | Azaindole derivatives, and preparation method and application thereof | 华东师范大学 | 2020-08-11 | — | — | CN | claimed |
| CN-111518095-A | Azaindole derivatives, and preparation method and application thereof | 华东师范大学 | 2020-08-11 | — | — | CN | disclosed |