⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11700851 | 0.77 | — | — | |
| SCHEMBL543992 | 0.77 | — | — | |
| SCHEMBL21431010 | 0.73 | ALDH1A1 (0.30) | — | |
| SCHEMBL2111409 | 0.71 | — | — | |
| SCHEMBL8856153 | 0.69 | LMNA (0.44) | — | |
| SCHEMBL4543302 | 0.69 | LMNA (0.34) | — | |
| SCHEMBL13001679 | 0.69 | TDP1 (0.38) | — | |
| SCHEMBL28203 | 0.69 | — | — | |
| SCHEMBL10383762 | 0.69 | — | — | |
| SCHEMBL11700212 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 885 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1514542-B1 | Medicinal composition comprising Tacrine or Donepezil for improving brain function. | TOYAMA CHEMICAL CO LTD (JP) | 2012-02-22 | — | — | EP | claimed |
| US-7432383-B2 | Intermediates for the hemisynthesis of taxanes and preparation processes therefor | SOCIETE D'ETUDE ET DE RECHERCHE EN INGENIERIE PHARMACEUTIQUE-SERIPHARM (FR) | 2008-10-07 | — | — | US | claimed |
| US-20070208185-A1 | Intermediates for the hemisynthesis of taxanes and preparation processes therefor | CHANTELOUP LUC | 2007-09-06 | — | — | US | claimed |
| US-7220871-B2 | Intermediates for the hemisynthesis of taxanes and preparation processes therefor | SOCIETE D'ETUDE ET DE RECHERCHE EN INGENIERIE PHARMACEUTIQUE SERIPHARM (FR) | 2007-05-22 | — | — | US | claimed |
| JP-2007501805-A | — | — | 2007-02-01 | — | — | JP | claimed |
| EP-1651638-A1 | PYRIDYL PIPERAZINYL UREAS | JANSSEN PHARMACEUTICA N.V. (BE) | 2006-05-03 | — | — | EP | claimed |
| US-20050222089-A1 | Intermediates for the hemisynthesis of taxanes and preparation processes therefor | CHANTELOUP LUC | 2005-10-06 | — | — | US | claimed |
| US-6888001-B2 | Selective modulators of the nicotinic acetylcholine receptor useful in the treatment of pain, Alzheimer's disease, memory loss or dementia or loss of motor function. | LEE JUNG S (US) | 2005-05-03 | — | — | US | claimed |
| US-20050049241-A1 | Pyridyl piperazinyl ureas | JANSSEN PHARMACEUTICA, N.V. (BE) | 2005-03-03 | — | — | US | claimed |
| WO-2005014580-A1 | PYRIDYL PIPERAZINYL UREAS | JANSSEN PHARMACEUTICA, N.V. (BE) | 2005-02-17 | — | — | WO | claimed |
| US-4185014-A | Kentenimine intermediates for 6α-methoxy-α-carboxy penicillins | BEECHAM GROUP LIMITED (GB) | 1980-01-22 | — | — | US | claimed |
| US-4129732-A | BACTERICIDE | PFIZER INC. (US) | 1978-12-12 | — | — | US | claimed |
| US-4121040-A | CEPHALOSPORIN ANTIBIOTICS | PFIZER INC. (US) | 1978-10-17 | — | — | US | claimed |
| US-4109083-A | CEPHALOSPORIN ANTIBIOTICS | PFIZER INC. (US) | 1978-08-22 | — | — | US | claimed |
| US-4097665-A | Diacylnucleosides and process for preparing the same | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JA) | 1978-06-27 | — | — | US | claimed |
| US-4039533-A | CEPHALOSPORINS | PFIZER INC. (US) | 1977-08-02 | — | — | US | claimed |
| US-4039532-A | BACTERICIDES | PFIZER INC. (US) | 1977-08-02 | — | — | US | claimed |
| US-4009159-A | PENICILLINS | FUJISAWA PHARMACEUTICAL CO., LTD. (JA) | 1977-02-22 | — | — | US | claimed |
| US-3993646-A | Process for the ring expansion of penicillins to cephalosporin compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JA) | 1976-11-23 | — | — | US | claimed |
| US-3978063-A | 1,2,3,4-Tetrahydroisoquinoline derivatives and the preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JA) | 1976-08-31 | — | — | US | claimed |