SCHEMBL2844204

SCHEMBL2844204

CC(=O)OCCCOCCCOC(C)=O

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.64
TSHR P16473 3/20 0.54
CHRM5 P08912 2/20 0.48
CHRM1 P11229 2/20 0.48
CHRM3 P20309 2/20 0.48
PGR P06401 1/20 0.48
CHRM2 P08172 1/20 0.48
CHRM4 P08173 1/20 0.48
HTR1A P08908 1/20 0.48
CHRNB2 P17787 1/20 0.48
TBXA2R P21731 1/20 0.48
CHRNB4 P30926 1/20 0.48
CHRNA3 P32297 1/20 0.48
CHRNA7 P36544 1/20 0.48
CHRNA4 P43681 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
CHRNA10 Q9GZZ6 1/20 0.48
CHRNA9 Q9UGM1 1/20 0.48
GALR3 O60755 2/20 0.46
GAA P10253 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30326816 1.00 ALDH1A1 (0.64) ALDH1A1TSHRCHRM5CHRM1CHRM3
SCHEMBL31243393 1.00 ALDH1A1 (0.64) ALDH1A1TSHRCHRM5CHRM1CHRM3
SCHEMBL30326809 1.00 ALDH1A1 (0.64) ALDH1A1TSHRCHRM5CHRM1CHRM3
SCHEMBL30326720 1.00 ALDH1A1 (0.64) ALDH1A1TSHRCHRM5CHRM1CHRM3
SCHEMBL6661477 0.94 ALDH1A1 (0.64) ALDH1A1TSHRCHRM5CHRM1CHRM3
SCHEMBL315271 0.91 ALDH1A1 (0.74) ALDH1A1TSHRCHRM5CHRM1CHRM3
SCHEMBL456552 0.91 ALDH1A1 (0.54) ALDH1A1TSHRCHRM5CHRM1CHRM3
SCHEMBL20963870 0.91 ALDH1A1 (0.54) ALDH1A1TSHRCHRM5CHRM1CHRM3
SCHEMBL2722997 0.91 ALDH1A1 (0.82) ALDH1A1TSHRCHRM5CHRM1CHRM3
SCHEMBL13034068 0.91 ALDH1A1 (0.82) ALDH1A1TSHRCHRM5CHRM1CHRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9242955-B2 Synthesis of cyclic carbonates UNIVERSITY OF YORK (GB) 2016-01-26 US disclosed
US-8809432-B2 Reusable print medium and method of manufacturing thereof OCE TECHNOLOGIES B.V. (NL) 2014-08-19 US disclosed
CN-101679343-B Synthesis of cyclic carbonates in the presence of dimeric aluminium (salen) catalysts UNIV NEWCASTLE 2014-06-18 CN disclosed
US-20130137805-A1 REUSABLE PRINT MEDIUM AND METHOD OF MANUFACTURING THEREOF OCE TECHNOLOGIES B.V. (NL) 2013-05-30 US disclosed
EP-2146977-B1 SYNTHESIS OF CYCLIC CARBONATES IN THE PRESENCE OF DIMERIC ALUMINIUM (SALEN) CATALYSTS UNIV NEWCASTLE (GB) 2012-11-14 EP disclosed
US-20100130752-A1 SYNTHESIS OF CYCLIC CARBONATES UNIVERSITY OF NEWCASTLE UPON TYNE (GB) 2010-05-27 US disclosed
CN-101679343-A Synthesis of cyclic carbonates in the presence of dimeric aluminium (salen) catalysts UNIV NEWCASTLE 2010-03-24 CN disclosed
EP-2146977-A1 SYNTHESIS OF CYCLIC CARBONATES IN THE PRESENCE OF DIMERIC ALUMINIUM (SALEN) CATALYSTS University Of Newcastle-Upon Tyne (GB) 2010-01-27 EP disclosed
WO-2008132474-A1 SYNTHESIS OF CYCLIC CARBONATES IN THE PRESENCE OF DIMERIC ALUMINIUM (SALEN) CATALYSTS UNIVERSITY OF NEWCASTLE UPON TYNE (GB) 2008-11-06 WO disclosed
WO-1993002044-A1 ACYCLIC 6-PHENYLSELENENYL PYRIMIDINE NUCLEOSIDES BAKER CUMMINS PHARMACEUTICALS, INC. (US) 1993-02-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100130752-A1 SYNTHESIS OF CYCLIC CARBONATES CA2, SCO2, CA7 ALDH1A1 3403/4885TSHR 4574/4885CHRM5 3133/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.