Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GUSB | P08236 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 7/20 | 0.61 |
| ▸ | MEN1 | O00255 | 6/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.61 |
| ▸ | LARS1 | Q9P2J5 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 5/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | RECQL | P46063 | 2/20 | 0.58 |
| ▸ | MAOB | P27338 | 5/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | MAOA | P21397 | 4/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.52 |
| ▸ | EGFR | P00533 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28443216 | 0.84 | MEN1 (0.58) | GUSBMAPTMEN1KMT2AGAA | |
| SCHEMBL28451541 | 0.84 | GAA (0.58) | GUSBMAPTMEN1KMT2ALARS1 | |
| SCHEMBL28451538 | 0.84 | MAOA (0.55) | GUSBMAPTMEN1KMT2AGAA | |
| SCHEMBL28897057 | 0.82 | MAOB (0.55) | MAPTMEN1KMT2AGAALMNA | |
| SCHEMBL4094409 | 0.74 | MEN1 (0.73) | GUSBMAPTMEN1KMT2ALARS1 | |
| SCHEMBL4094410 | 0.74 | MEN1 (0.73) | GUSBMAPTMEN1KMT2ALARS1 | |
| SCHEMBL4099204 | 0.73 | MAPT (1.00) | GUSBMAPTMEN1KMT2ALARS1 | |
| SCHEMBL4099199 | 0.73 | MAPT (1.00) | GUSBMAPTMEN1KMT2ALARS1 | |
| SCHEMBL30294200 | 0.69 | MAPT (0.74) | MAPTMEN1KMT2AGAALMNA | |
| SCHEMBL12643697 | 0.69 | MAPT (1.00) | MAPTMEN1KMT2AGAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111533696-A | Benzimidazole derivative, benzothiophene derivative, and preparation method and application thereof | 苏州大学 | 2020-08-14 | — | — | CN | disclosed |