Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 6/20 | 0.58 |
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | GUSB | P08236 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | MAOA | P21397 | 6/20 | 0.55 |
| ▸ | MAOB | P27338 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | CASP3 | P42574 | 1/20 | 0.55 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.55 |
| ▸ | RELA | Q04206 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28443216 | 0.89 | MEN1 (0.58) | GAAMAPTRAB9ANPC1GUSB | |
| SCHEMBL28451538 | 0.89 | MAOA (0.55) | GAAMAPTRAB9AMAPK1NPC1 | |
| SCHEMBL28897057 | 0.86 | MAOB (0.55) | GAAMAPTRAB9ANPC1MEN1 | |
| SCHEMBL28442631 | 0.84 | GUSB (0.61) | GAAMAPTRAB9AMAPK1NPC1 | |
| SCHEMBL17150984 | 0.80 | MAPT (0.76) | GAAMAPTRAB9AMAPK1NPC1 | |
| SCHEMBL18980779 | 0.80 | MAPT (0.76) | GAAMAPTRAB9AMAPK1NPC1 | |
| SCHEMBL18980780 | 0.80 | MAPT (0.76) | GAAMAPTRAB9AMAPK1NPC1 | |
| SCHEMBL16742020 | 0.76 | GUSB (0.64) | GAAMAPTRAB9AMAPK1NPC1 | |
| SCHEMBL16742019 | 0.76 | GUSB (0.64) | GAAMAPTRAB9AMAPK1NPC1 | |
| SCHEMBL8265955 | 0.72 | MAPT (0.66) | GAAMAPTRAB9AMAPK1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111533696-A | Benzimidazole derivative, benzothiophene derivative, and preparation method and application thereof | 苏州大学 | 2020-08-14 | — | — | CN | disclosed |