Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 3/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CTSD | P07339 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | DRD3 | P35462 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28452179 | 0.96 | KMT2A (0.37) | MEN1KMT2AALDH1A1KDM4ECNR1 | |
| SCHEMBL28457314 | 0.81 | GAA (0.41) | MEN1KMT2AALDH1A1KDM4ESLC6A2 | |
| SCHEMBL28453362 | 0.81 | KMT2A (0.46) | MEN1KMT2AALDH1A1KDM4EGAA | |
| SCHEMBL28445944 | 0.79 | ALDH1A1 (0.46) | MEN1KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL28452276 | 0.79 | MEN1 (0.39) | MEN1KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL28451755 | 0.79 | MAPT (0.46) | MEN1KMT2AALDH1A1KDM4ESLC6A2 | |
| SCHEMBL28898040 | 0.79 | MEN1 (0.39) | MEN1KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL28451977 | 0.78 | MAPT (0.47) | MEN1KMT2AALDH1A1HPGDGAA | |
| SCHEMBL28447937 | 0.75 | AR (0.38) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL28453210 | 0.75 | TSHR (0.43) | MEN1KMT2AALDH1A1KDM4ESLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110156789-B | Synthetic method of azacyclo-quinazoline compound | 东华理工大学 | 2020-09-04 | — | — | CN | disclosed |