Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 2/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GRM8 | O00222 | 1/20 | 0.44 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5764883 | 0.83 | TRPA1 (0.54) | SLC6A2SLC6A3SLC6A4KDM4EKMT2A | |
| SCHEMBL29539584 | 0.83 | KDM4E (0.56) | GRM4SLC6A2SLC6A3SLC6A4KDM4E | |
| SCHEMBL18984732 | 0.83 | KDM4E (0.56) | GRM4SLC6A2SLC6A3SLC6A4KDM4E | |
| SCHEMBL6949228 | 0.81 | ALDH1A1 (0.59) | GRM4SLC6A2SLC6A3SLC6A4KMT2A | |
| SCHEMBL4034223 | 0.81 | GRM4 (0.51) | GRM4KDM4EGRM8GRM7BLM | |
| SCHEMBL4799379 | 0.81 | GRM4 (0.48) | GRM4KDM4EGRM8GRM7BLM | |
| SCHEMBL28443642 | 0.80 | ALDH1A1 (0.44) | GRM4KDM4EBLMALDH1A1ALOX15 | |
| SCHEMBL28440382 | 0.79 | GRM4 (0.47) | GRM4KDM4EGRM8GRM7BLM | |
| SCHEMBL3288850 | 0.77 | KDM4E (0.47) | GRM4KDM4EKMT2AL3MBTL1SMN1; SMN2 | |
| SCHEMBL7020782 | 0.77 | KDM4E (0.41) | GRM4KDM4EGRM8GRM7BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107011251-B | Synthesis method and application of 2- (2-chlorophenoxy) pyridine compound | 温州医科大学 | 2020-08-11 | — | — | CN | disclosed |