SCHEMBL28443197

SCHEMBL28443197

BC1CCCC1.CN1CCCc2ccccc21

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.46
ALDH1A1 P00352 2/20 0.46
KMT2A Q03164 2/20 0.46
POLB P06746 1/20 0.46
GAA P10253 1/20 0.45
MAPT P10636 1/20 0.45
HPGD P15428 1/20 0.45
NOTUM Q6P988 1/20 0.44
TSHR P16473 1/20 0.43
SMN1; SMN2 Q16637 2/20 0.42
SIGMAR1 Q99720 1/20 0.42
CHRM2 P08172 6/20 0.42
CHRM4 P08173 6/20 0.42
CHRM1 P11229 6/20 0.42
CHRM3 P20309 6/20 0.42
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
CYP2D6 P10635 1/20 0.40
MGLL Q99685 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29699544 0.86 ALDH1A1 (0.58) MEN1ALDH1A1KMT2AGAAMAPT
SCHEMBL159025 0.86 ALDH1A1 (0.58) MEN1ALDH1A1KMT2AGAAMAPT
SCHEMBL174780 0.81 ALDH1A1 (0.51) MEN1ALDH1A1KMT2AGAAMAPT
SCHEMBL23601610 0.79 MEN1 (0.50) MEN1ALDH1A1KMT2AGAAMAPT
SCHEMBL12013900 0.79 MEN1 (0.50) MEN1ALDH1A1KMT2AGAAMAPT
SCHEMBL142091 0.74 ALDH1A1 (0.59) MEN1ALDH1A1KMT2APOLBMAPT
Bromide SCHEMBL29602074 0.73 ALDH1A1 (0.57) MEN1ALDH1A1KMT2APOLBMAPT
Hydrochloric Acid SCHEMBL22582303 0.73 ALDH1A1 (0.57) MEN1ALDH1A1KMT2APOLBMAPT
SCHEMBL18542614 0.72 TSHR (0.57) TSHRSIGMAR1
SCHEMBL23188902 0.70 NOTUM (0.46) MEN1ALDH1A1KMT2AGAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107922382-B Novel ligand compound and transition metal compound LG化学株式会社 2020-07-07 CN disclosed