SCHEMBL29699544

SCHEMBL29699544

CN1CCCc2ccccc21

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.58
MEN1 O00255 4/20 0.58
KMT2A Q03164 4/20 0.58
NOTUM Q6P988 1/20 0.55
SMN1; SMN2 Q16637 3/20 0.53
SIGMAR1 Q99720 1/20 0.53
MAPT P10636 4/20 0.51
HPGD P15428 2/20 0.51
GAA P10253 1/20 0.51
USP2 O75604 1/20 0.50
CDK4 P11802 1/20 0.50
ALOX15 P16050 1/20 0.50
CCND1 P24385 1/20 0.50
MGLL Q99685 1/20 0.49
TSHR P16473 1/20 0.47
MAPK1 P28482 1/20 0.47
CHRM2 P08172 2/20 0.45
CHRM4 P08173 2/20 0.45
CHRM1 P11229 2/20 0.45
CHRM3 P20309 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL159025 1.00 ALDH1A1 (0.58) ALDH1A1MEN1KMT2ANOTUMSMN1; SMN2
SCHEMBL174780 0.94 ALDH1A1 (0.51) ALDH1A1MEN1KMT2ANOTUMSMN1; SMN2
SCHEMBL23601610 0.92 MEN1 (0.50) ALDH1A1MEN1KMT2ANOTUMSMN1; SMN2
SCHEMBL12013900 0.92 MEN1 (0.50) ALDH1A1MEN1KMT2ANOTUMSMN1; SMN2
SCHEMBL142091 0.86 ALDH1A1 (0.59) ALDH1A1MEN1KMT2ANOTUMSMN1; SMN2
SCHEMBL28443197 0.86 MEN1 (0.46) ALDH1A1MEN1KMT2ANOTUMSMN1; SMN2
Hydrochloric Acid SCHEMBL22582303 0.84 ALDH1A1 (0.57) ALDH1A1MEN1KMT2ANOTUMSMN1; SMN2
Bromide SCHEMBL29602074 0.84 ALDH1A1 (0.57) ALDH1A1MEN1KMT2ANOTUMSMN1; SMN2
SCHEMBL23188902 0.81 NOTUM (0.46) ALDH1A1MEN1KMT2ANOTUMSMN1; SMN2
SCHEMBL16707769 0.79 TP53 (0.42) ALDH1A1MEN1KMT2AMAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118125962-A Method for preparing 2-aminomethylindoline-3-carboxylic acid from carbon dioxide 常州大学 2024-06-04 CN claimed
CN-117160451-A Platinum-tin bimetallic catalyst for quinoline compound reduction methylation and preparation method and application thereof 浙江大学衢州研究院 2023-12-05 CN claimed
EP-4635565-A1 PRENYLATED TETRAHYDROQUINOLINES AND QUINOLINES WITH PPAR AGONIST ACTIVITY Fundación para la Investigación del Hospital Clínico de la Comunidad Valenciana (INCLIVA) (ES) 2025-10-22 EP disclosed
US-12344600-B2 c-Myc mRNA translation modulators and uses thereof in the treatment of cancer ANIMA BIOTECH INC. (US) 2025-07-01 US disclosed
CN-120136645-A Synthesis method and application of aromatic amine and indole compound containing hexafluoroisopropanol structural unit 海南大学 2025-06-13 CN disclosed
US-20250109128-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2025-04-03 US disclosed
CN-118382612-A Method for producing blocked isocyanate compound and method for producing isocyanate compound 旭化成株式会社 2024-07-23 CN disclosed
CN-118290350-A Heteroaryl and bisheteroaryl derivatives for the treatment of iron death-related disorders 协同医药发展有限公司 2024-07-05 CN disclosed
US-20240199638-A1 GLUTARIMIDES FOR MEDICAL TREATMENT C4 THERAPEUTICS, INC. (US) 2024-06-20 US disclosed
CN-118125962-A Method for preparing 2-aminomethylindoline-3-carboxylic acid from carbon dioxide 常州大学 2024-06-04 CN disclosed
CN-116239529-B Preparation method of N-methyltetrahydroquinoline alkaloid with participation of carbon dioxide 山西大学 2024-05-24 CN disclosed
WO-2023132841-A1 IMPROVING OUTCOMES AND RESPONSE TIMES FOR PATIENTS IN CRITICAL CARE SETTINGS POSTREL RICHARD (US) 2023-07-13 WO disclosed
WO-2023106377-A1 METHOD FOR PRODUCING BLOCKED ISOCYANATE COMPOUND AND METHOD FOR PRODUCING ISOCYANATE COMPOUND 旭化成株式会社 2023-06-15 WO disclosed
CN-116239529-A Preparation method of N-methyltetrahydroquinoline alkaloid with participation of carbon dioxide 山西大学 2023-06-09 CN disclosed
CN-116239529-A Preparation method of N-methyltetrahydroquinoline alkaloid with participation of carbon dioxide 山西大学 2023-06-09 CN disclosed
CN-115160098-B Oxygen-containing compound deoxidization methylation method 中国科学院兰州化学物理研究所 2023-06-06 CN disclosed
US-20230088214-A1 GLYCOLATE OXIDASE INHIBITORS FOR THE TREATMENT OF DISEASE BIOMARIN PHARMACEUTICAL INC. (US) 2023-03-23 US disclosed
US-20230089374-A1 GLYCOLATE OXIDASE INHIBITORS FOR THE TREATMENT OF DISEASE BIOMARIN PHARMACEUTICAL INC. (US) 2023-03-23 US disclosed
US-20230079913-A1 GLYCOLATE OXIDASE INHIBITORS FOR THE TREATMENT OF DISEASE BIOMARIN PHARMACEUTICAL INC. (US) 2023-03-16 US disclosed
US-11384055-B2 Glycolate oxidase inhibitors for the treatment of disease BIOMARIN PHARMACEUTICAL INC. (US) 2022-07-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230079913-A1 GLYCOLATE OXIDASE INHIBITORS FOR THE TREATMENT OF DISEASE XDH, PNPO, AGXT ALDH1A1 481/4885MEN1 2988/4885KMT2A 4011/4885
US-20230088214-A1 GLYCOLATE OXIDASE INHIBITORS FOR THE TREATMENT OF DISEASE XDH, PNPO, AGXT ALDH1A1 552/4885MEN1 2927/4885KMT2A 3699/4885
US-11384055-B2 Glycolate oxidase inhibitors for the treatment of disease XDH, PNPO, AGXT ALDH1A1 481/4885MEN1 2988/4885KMT2A 4011/4885
US-20230089374-A1 GLYCOLATE OXIDASE INHIBITORS FOR THE TREATMENT OF DISEASE XDH, PNPO, AGXT ALDH1A1 481/4885MEN1 2988/4885KMT2A 4011/4885
US-20240199638-A1 GLUTARIMIDES FOR MEDICAL TREATMENT CRBN, GCDH, GCLC ALDH1A1 1593/4885MEN1 2114/4885KMT2A 1703/4885
US-12344600-B2 c-Myc mRNA translation modulators and uses thereof in the treatment of cancer MYC, MYCBP, MYCBP2 ALDH1A1 4471/4885MEN1 1569/4885KMT2A 1404/4885
US-20250109128-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER MYC, MYCBP, MYCBP2 ALDH1A1 4471/4885MEN1 1569/4885KMT2A 1404/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.