Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | CASP1 | P29466 | 2/20 | 0.36 |
| ▸ | CASP7 | P55210 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CASP6 | P55212 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28451755 | 0.85 | MAPT (0.46) | KMT2ASLC6A2MAPTTSHRNPSR1 | |
| SCHEMBL28453362 | 0.84 | KMT2A (0.46) | KMT2AMAPTALDH1A1MEN1CASP1 | |
| SCHEMBL28451750 | 0.84 | ALDH1A1 (0.50) | KMT2AMAPTTSHRALDH1A1MEN1 | |
| SCHEMBL28448226 | 0.79 | ALDH1A1 (0.45) | KMT2AMAPTTSHRALDH1A1MEN1 | |
| SCHEMBL28449247 | 0.79 | PDE4A (0.40) | MAPTALDH1A1HSD17B10GAA | |
| SCHEMBL28452276 | 0.77 | MEN1 (0.39) | KMT2AMAPTALDH1A1MEN1CASP1 | |
| SCHEMBL28457314 | 0.77 | GAA (0.41) | KMT2ASLC6A2MAPTTSHRNPSR1 | |
| SCHEMBL28445944 | 0.77 | ALDH1A1 (0.46) | KMT2AMAPTALDH1A1MEN1CASP1 | |
| SCHEMBL28898040 | 0.77 | MEN1 (0.39) | KMT2AMAPTALDH1A1MEN1CASP1 | |
| SCHEMBL28453210 | 0.76 | TSHR (0.43) | KMT2ASLC6A2MAPTTSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110156789-B | Synthetic method of azacyclo-quinazoline compound | 东华理工大学 | 2020-09-04 | — | — | CN | disclosed |