Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.41 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 2/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28435242 | 0.88 | MAPT (0.52) | DPP4PLA2G2AMAPTKDM4EDPP8 | |
| SCHEMBL28443347 | 0.82 | GAA (0.48) | PLA2G2AMAPTKDM4EABCB11GAA | |
| SCHEMBL8268871 | 0.80 | MAPT (0.47) | DPP4PLA2G2AMAPTKDM4EDPP8 | |
| SCHEMBL2704427 | 0.75 | PLA2G2A (0.44) | DPP4PLA2G2AMAPTKDM4ECYP3A4 | |
| SCHEMBL11262514 | 0.72 | GAA (0.45) | PLA2G2AMAPTKDM4EGAAPOLB | |
| SCHEMBL295426 | 0.70 | MAPT (0.48) | DPP4MAPTKDM4EDPP8DPP9 | |
| SCHEMBL2706201 | 0.70 | DPP4 (0.64) | DPP4CYP3A4DPP8DPP9 | |
| SCHEMBL6949718 | 0.70 | GAA (0.56) | MAPTKDM4EABCB11CYP3A4CNR1 | |
| SCHEMBL30686655 | 0.70 | GAA (0.56) | MAPTKDM4EABCB11CYP3A4CNR1 | |
| SCHEMBL31231118 | 0.70 | GAA (0.56) | MAPTKDM4EABCB11CYP3A4CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111423362-A | Preparation method of two high-purity clevidipine butyrate impurities | 山东省药学科学院 | 2020-07-17 | — | — | CN | disclosed |