Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.37 |
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | MEN1 | O00255 | 5/20 | 0.37 |
| ▸ | GAA | P10253 | 5/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | ATM | Q13315 | 2/20 | 0.35 |
| ▸ | APAF1 | O14727 | 1/20 | 0.35 |
| ▸ | TDP2 | O95551 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | CASP6 | P55212 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL257285 | 0.83 | KDM4E (0.44) | KMT2AMAPTMEN1GAANPC1 | |
| SCHEMBL19691966 | 0.81 | ALDH1A1 (0.44) | KMT2AMAPTGAAKDM4EALDH1A1 | |
| SCHEMBL16512963 | 0.78 | ALDH1A1 (0.42) | KMT2AMAPTGAAKDM4EALDH1A1 | |
| SCHEMBL21712348 | 0.77 | CA12 (0.49) | KMT2AMAPTMEN1GAANPC1 | |
| SCHEMBL29009066 | 0.77 | MEN1 (0.40) | KMT2AMAPTMEN1GAANPC1 | |
| SCHEMBL28451735 | 0.77 | NPC1 (0.41) | KMT2AMAPTMEN1GAANPC1 | |
| SCHEMBL21712220 | 0.76 | GAA (0.49) | KMT2AMAPTMEN1GAANPC1 | |
| SCHEMBL28447536 | 0.76 | L3MBTL1 (0.51) | KMT2AMAPTMEN1RAB9AKDM4E | |
| SCHEMBL1855577 | 0.74 | ALDH1A1 (0.44) | KMT2AMAPTGAAKDM4EALDH1A1 | |
| SCHEMBL27974 | 0.73 | DPP4 (0.41) | MAPTGAASMN1; SMN2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111606928-A | Azacyclodiketone compound and preparation method thereof | 维清生物科技(上海)有限公司 | 2020-09-01 | — | — | CN | disclosed |