Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.55 |
| ▸ | APP | P05067 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.48 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | LY96 | Q9Y6Y9 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28445243 | 1.00 | HDAC8 (0.55) | HDAC8APPALDH1A1MEN1MAPT | |
| SCHEMBL16878990 | 0.93 | APP (0.52) | HDAC8APPALDH1A1AKR1B10AKR1B1 | |
| SCHEMBL8007239 | 0.92 | MAPT (0.59) | HDAC8APPALDH1A1MEN1MAPT | |
| SCHEMBL2226678 | 0.92 | MAPT (0.59) | HDAC8APPALDH1A1MEN1MAPT | |
| SCHEMBL25288435 | 0.87 | HDAC8 (0.58) | HDAC8ALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL7205018 | 0.87 | HDAC8 (0.58) | HDAC8ALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL1232746 | 0.85 | APP (0.53) | HDAC8APPALDH1A1AKR1B10AKR1B1 | |
| SCHEMBL4531147 | 0.85 | APP (0.53) | HDAC8APPALDH1A1AKR1B10AKR1B1 | |
| SCHEMBL3782592 | 0.82 | ALDH1A1 (0.58) | APPALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL5151394 | 0.81 | MAPT (0.58) | HDAC8ALDH1A1MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106309421-B | Pharmaceutical composition and cosmetic composition | 沃凯索法株式会社 | 2020-08-25 | — | — | CN | disclosed |