SCHEMBL7205018

SCHEMBL7205018

CCOC(=O)C=Cc1ccc(OC)cc1OCC

nearest known ligand 0.58

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HDAC8 Q9BY41 6/20 0.58
MAPT P10636 3/20 0.57
ALDH1A1 P00352 3/20 0.57
MEN1 O00255 1/20 0.57
KMT2A Q03164 1/20 0.57
LY96 Q9Y6Y9 1/20 0.53
TNFRSF1A P19438 1/20 0.52
FDPS P14324 1/20 0.51
SMN1; SMN2 Q16637 2/20 0.50
MAOB P27338 1/20 0.50
NPC1 O15118 1/20 0.50
RAB9A P51151 1/20 0.50
ESR1 P03372 1/20 0.50
KDM4E B2RXH2 1/20 0.49
CYP1A1 P04798 1/20 0.49
CYP1B1 Q16678 1/20 0.49
BACE1 P56817 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25288435 1.00 HDAC8 (0.58) HDAC8MAPTALDH1A1MEN1KMT2A
SCHEMBL4592405 0.92 MAPT (0.68) MAPTALDH1A1MEN1KMT2ALY96
SCHEMBL4592398 0.92 MAPT (0.68) MAPTALDH1A1MEN1KMT2ALY96
SCHEMBL28445241 0.87 HDAC8 (0.55) HDAC8MAPTALDH1A1MEN1KMT2A
SCHEMBL28445243 0.87 HDAC8 (0.55) HDAC8MAPTALDH1A1MEN1KMT2A
SCHEMBL18538460 0.87 HDAC8 (0.79) HDAC8MAPTALDH1A1MEN1KMT2A
SCHEMBL751457 0.86 MAPT (0.60) HDAC8MAPTALDH1A1MEN1KMT2A
SCHEMBL751456 0.86 MAPT (0.60) HDAC8MAPTALDH1A1MEN1KMT2A
Anthranilic Acid SCHEMBL28178203 0.86 HDAC8 (0.53) HDAC8MAPTALDH1A1MEN1KMT2A
SCHEMBL10669860 0.84 MAPT (0.61) MAPTALDH1A1MEN1KMT2ALY96

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0501714-B1 Cationic compositions for skin UNILEVER PLC (GB) 1997-05-02 EP claimed
US-5169624-A Quaternary ammonium phosphate ester, cationic polysaccharide, sunscreen agent CHESEBROUGH-POND'S USA CO., DIVISION OF CONOPCO, INC. (US) 1992-12-08 US claimed
EP-0501714-A2 Cationic compositions for skin UNILEVER PLC (GB) 1992-09-02 EP claimed
US-20230172194-A1 COMPOSITION INCLUDING EFFERVESCENT AGENTS, BIOSTIMULANT, NUTRIENT, AND PESTICIDE ROBBINS JEFFREY HANSON (US) 2023-06-08 US disclosed
EP-3717607-A1 CLEANSING COMPOSITIONS AND USE THEREOF Colgate-Palmolive Company (US) 2020-10-07 EP disclosed
CN-106309421-B Pharmaceutical composition and cosmetic composition 沃凯索法株式会社 2020-08-25 CN disclosed
EP-3331615-A1 PERSONAL CARE COMPOSITIONS COMPRISING POLYMERS DERIVED FROM VINYL ALCOHOL ETHERS AND APPLICATIONS THEREOF ISP Investments LLC (US) 2018-06-13 EP disclosed
WO-2017123572-A1 BLOCK COPOLYMERS COMPRISING REPEATING UNITS DERIVED FROM MONOMERS COMPRISING LACTAM AND ACRYLOYL MOIETIES AND HYDROPHOBIC MONOMERS, COMPOSITIONS, AND APPLICATIONS THEREOF ISP INVESTMENTS LLC (US) 2017-07-20 WO disclosed
WO-2017024016-A1 PERSONAL CARE COMPOSITIONS COMPRISING POLYMERS DERIVED FROM VINYL ALCOHOL ETHERS AND APPLICATIONS THEREOF ISP INVESTMENTS LLC (US) 2017-02-09 WO disclosed
EP-0828473-B1 A COSMETIC PRODUCT TO PREVENT AND CORRECT SKIN DAMAGE UNILEVER NV (NL) 2003-07-09 EP disclosed
EP-0547864-B1 Self-tanner cosmetic composition UNILEVER PLC (GB) 1998-09-09 EP disclosed
EP-0828473-A1 A COSMETIC PRODUCT TO PREVENT AND CORRECT SKIN DAMAGE UNILEVER N.V. (NL) 1998-03-18 EP disclosed
EP-0501714-B1 Cationic compositions for skin UNILEVER PLC (GB) 1997-05-02 EP disclosed
WO-1996037179-A1 A COSMETIC PRODUCT TO PREVENT AND CORRECT SKIN DAMAGE UNILEVER PLC (GB) 1996-11-28 WO disclosed
WO-1994020066-A1 SUNSCREEN COMPOSITION UNILEVER PLC (GB) 1994-09-15 WO disclosed
US-4293542-A PYRIDINE N-OXIDE DERIVATIVE L'OREAL (FR) 1981-10-06 US disclosed
US-4228151-A QUINOXALINE DIOXIDE L'OREAL (FR) 1980-10-14 US disclosed