Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CCR1 | P32246 | 1/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.33 |
| ▸ | PARP1 | P09874 | 2/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.33 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | PGK1 | P00558 | 1/20 | 0.32 |
| ▸ | PGK2 | P07205 | 1/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28803087 | 0.87 | MEN1 (0.36) | MEN1KMT2AHRH4ADORA2APARP1 | |
| SCHEMBL14842178 | 0.84 | MEN1 (0.41) | MEN1KMT2ACCR1HRH4ADORA2A | |
| SCHEMBL27813484 | 0.83 | PARP1 (0.50) | MEN1KMT2AHRH4ADORA2APARP1 | |
| SCHEMBL27961424 | 0.83 | MEN1 (0.40) | MEN1KMT2AHRH4ADORA2APARP1 | |
| SCHEMBL10768300 | 0.81 | MEN1 (0.52) | MEN1KMT2APARP1NPSR1F2 | |
| SCHEMBL5200121 | 0.77 | MEN1 (0.44) | MEN1KMT2APARP1MTNR1AMTNR1B | |
| SCHEMBL12503433 | 0.76 | MEN1 (0.35) | MEN1KMT2AHRH4ADORA2APARP1 | |
| SCHEMBL29202909 | 0.75 | MEN1 (0.34) | MEN1KMT2AADORA2APARP1MAPK8 | |
| SCHEMBL20557225 | 0.74 | MEN1 (0.45) | MEN1KMT2APARP1F2F10 | |
| SCHEMBL28677153 | 0.73 | ALDH1A1 (0.46) | MEN1KMT2APARP1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116888125-B | TYK2 inhibitor and application thereof | 上海齐鲁制药研究中心有限公司 | 2024-04-12 | — | — | CN | disclosed |
| CN-112624965-B | Novel oxime derivative and application thereof in agriculture | 东莞市东阳光农药研发有限公司 | 2024-01-16 | — | — | CN | disclosed |
| CN-116888125-A | TYK2 inhibitor and application thereof | 上海齐鲁制药研究中心有限公司 | 2023-10-13 | — | — | CN | disclosed |
| CN-116514728-A | Quinazoline derivative and application thereof | 赛诺哈勃药业（成都）有限公司 | 2023-08-01 | — | — | CN | disclosed |
| CN-112110894-B | Phenyl oxime derivative and preparation method and application thereof | 东莞市东阳光农药研发有限公司 | 2023-04-07 | — | — | CN | disclosed |
| CN-112624965-A | Novel oxime derivative and application thereof in agriculture | 东莞市东阳光农药研发有限公司 | 2021-04-09 | — | — | CN | disclosed |
| CN-112110894-A | Phenyl oxime derivative and preparation method and application thereof | 东莞市东阳光农药研发有限公司 | 2020-12-22 | — | — | CN | disclosed |
| CN-111630044-A | Oximino-tetrazole derivatives and application thereof in agriculture | 东莞市东阳光农药研发有限公司 | 2020-09-04 | — | — | CN | disclosed |
| CN-110452220-B | Oxime derivatives and their use in agriculture | 东莞市东阳光农药研发有限公司 | 2020-08-14 | — | — | CN | disclosed |