Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 5/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10768300 | 0.86 | MEN1 (0.52) | ALDH1A1L3MBTL1MEN1KMT2AF2 | |
| SCHEMBL1732930 | 0.82 | L3MBTL1 (0.45) | ALDH1A1L3MBTL1MEN1KMT2AF2 | |
| SCHEMBL21801447 | 0.81 | L3MBTL1 (0.48) | ALDH1A1L3MBTL1KMT2AF2CYP3A4 | |
| SCHEMBL20557225 | 0.78 | MEN1 (0.45) | MEN1KMT2AF2MAPTSMN1; SMN2 | |
| SCHEMBL9326030 | 0.78 | L3MBTL1 (0.52) | ALDH1A1L3MBTL1MEN1KMT2AF2 | |
| SCHEMBL21115271 | 0.77 | MEN1 (0.44) | MEN1KMT2AMAPTPARP1 | |
| SCHEMBL5200121 | 0.77 | MEN1 (0.44) | ALDH1A1MEN1KMT2AF2HPGD | |
| SCHEMBL9324812 | 0.77 | NPSR1 (0.47) | ALDH1A1L3MBTL1MEN1KMT2AF2 | |
| SCHEMBL4093370 | 0.77 | L3MBTL1 (0.44) | ALDH1A1L3MBTL1MEN1KMT2AF2 | |
| SCHEMBL20815627 | 0.75 | L3MBTL1 (0.47) | ALDH1A1L3MBTL1MEN1KMT2AF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113880866-B | Aza-tetrahydronaphthyridine compound, preparation method thereof, pharmaceutical composition and application thereof | 上海维申医药有限公司 | 2022-09-27 | — | — | CN | disclosed |
| CN-113880866-A | Aza-tetrahydronaphthyridine compound, preparation method thereof, pharmaceutical composition and application thereof | 上海维申医药有限公司 | 2022-01-04 | — | — | CN | disclosed |