Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL28445447

Cc1ccc2c(c1C)Cc1cc([N+](=O)[O-])ccc1S2.N

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.45
TDP1 Q9NUW8 3/20 0.45
TSHR P16473 2/20 0.45
CYP3A4 P08684 3/20 0.42
MAPT P10636 3/20 0.40
TLR9 Q9NR96 2/20 0.40
RAB9A P51151 2/20 0.40
PGR P06401 2/20 0.40
MEN1 O00255 1/20 0.40
LMNA P02545 1/20 0.40
KMT2A Q03164 1/20 0.40
HSP90AA1 P07900 1/20 0.40
CRHBP P24387 1/20 0.38
CRHR2 Q13324 1/20 0.38
NPC1 O15118 1/20 0.37
PDE2A O00408 1/20 0.37
PDE5A O76074 1/20 0.37
ALOX15 P16050 1/20 0.37
NFKB1 P19838 1/20 0.37
APEX1 P27695 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28182755 0.79 HSP90AA1 (0.57) ALDH1A1TDP1TSHRCYP3A4MAPT
SCHEMBL9641625 0.73 TDP2 (0.46) ALDH1A1TDP1TSHRCYP3A4MAPT
SCHEMBL28445445 0.69 TLR9 (0.44) ALDH1A1TDP1TSHRCYP3A4MAPT
SCHEMBL8204482 0.69 BLM (0.62) ALDH1A1MAPTTLR9RAB9AMEN1
SCHEMBL14076432 0.68 HSP90AA1 (0.65) ALDH1A1TDP1TSHRCYP3A4MAPT
SCHEMBL9698085 0.67 SNCA (0.56) ALDH1A1TDP1TSHRCYP3A4LMNA
SCHEMBL1144860 0.67 SNCA (0.56) ALDH1A1TDP1TSHRCYP3A4LMNA
SCHEMBL11015193 0.66 SNCA (0.51) ALDH1A1TDP1CYP3A4MAPTTLR9
SCHEMBL10367841 0.66 TDP2 (0.40) ALDH1A1TDP1TSHRMAPTTLR9
SCHEMBL987760 0.65 TLR9 (0.79) ALDH1A1TDP1TSHRCYP3A4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109270712-B Liquid crystal film and preparation method and application thereof 北京化工大学 2020-07-14 CN claimed
CN-109270712-B Liquid crystal film and preparation method and application thereof 北京化工大学 2020-07-14 CN disclosed