Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.57 |
| ▸ | LMNA | P02545 | 4/20 | 0.57 |
| ▸ | RAB9A | P51151 | 9/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.54 |
| ▸ | BACE1 | P56817 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 7/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | HTT | P42858 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | CASP1 | P29466 | 1/20 | 0.53 |
| ▸ | GFER | P55789 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28448687 | 0.91 | MGAM (0.54) | TSHRMAPK1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL28453972 | 0.91 | MAPK1 (0.54) | TSHRMAPK1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL28453905 | 0.89 | ALDH1A1 (0.57) | TSHRMAPK1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL28452384 | 0.88 | PTK2 (0.56) | TSHRMAPK1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL28453935 | 0.88 | PTK2 (0.56) | TSHRMAPK1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL28447025 | 0.87 | PTK2 (0.58) | TSHRMAPK1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL28448690 | 0.86 | PTK2 (0.56) | TSHRMAPK1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL3077568 | 0.84 | CYP1A2 (0.69) | TSHRMAPK1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL28446500 | 0.84 | TSHR (0.58) | TSHRMAPK1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL28445488 | 0.81 | MAPK1 (0.52) | TSHRMAPK1LMNARAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106916150-B | 1,3, 4-oxadiazole-2-methylthio-benzothiazole derivative, preparation method and application thereof | 中国科学院上海药物研究所 | 2020-08-25 | — | — | CN | claimed |
| CN-106916150-B | 1,3, 4-oxadiazole-2-methylthio-benzothiazole derivative, preparation method and application thereof | 中国科学院上海药物研究所 | 2020-08-25 | — | — | CN | disclosed |