Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 14/20 | 0.56 |
| ▸ | TP53 | P04637 | 5/20 | 0.56 |
| ▸ | LMNA | P02545 | 5/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28449581 | 0.90 | MAPT (0.58) | MAPTTP53LMNATSHRSMN1; SMN2 | |
| SCHEMBL28898452 | 0.88 | MAPT (0.56) | MAPTTP53LMNATSHRSMN1; SMN2 | |
| SCHEMBL28457838 | 0.88 | MAPT (0.56) | MAPTTP53LMNATSHRSMN1; SMN2 | |
| SCHEMBL28457842 | 0.86 | MAPT (0.55) | MAPTTP53LMNATSHRSMN1; SMN2 | |
| SCHEMBL28457871 | 0.85 | LMNA (0.53) | MAPTTP53LMNATSHRSMN1; SMN2 | |
| SCHEMBL19367498 | 0.85 | MAPT (0.63) | MAPTTP53LMNATSHRSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL28454395 | 0.85 | LMNA (0.52) | MAPTTP53LMNATSHRSMN1; SMN2 | |
| SCHEMBL28456325 | 0.85 | MAPT (0.53) | MAPTTP53LMNATSHRSMN1; SMN2 | |
| SCHEMBL28460354 | 0.84 | LMNA (0.52) | MAPTTP53LMNATSHRSMN1; SMN2 | |
| SCHEMBL15076711 | 0.84 | CYP3A4 (0.67) | MAPTTP53LMNATSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109879799-B | Sulfamoyl benzamide compound containing 4-carbonyloxypiperidine and preparation method thereof | 浙江司太立制药股份有限公司 | 2020-08-11 | — | — | CN | disclosed |