Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | PPARG | P37231 | 2/20 | 0.46 |
| ▸ | NCOA2 | Q15596 | 2/20 | 0.46 |
| ▸ | NCOA1 | Q15788 | 2/20 | 0.46 |
| ▸ | APAF1 | O14727 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MC4R | P32245 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13203110 | 0.91 | MEN1 (0.52) | AGTR1ALDH1A1MAPTKDM4EKMT2A | |
| SCHEMBL13203307 | 0.90 | MEN1 (0.50) | AGTR1ALDH1A1MAPTKDM4EKMT2A | |
| SCHEMBL28026305 | 0.89 | MEN1 (0.53) | AGTR1ALDH1A1MAPTKDM4EKMT2A | |
| SCHEMBL29724219 | 0.85 | MAOB (0.46) | MCL1ALDH1A1MAPTKDM4EKMT2A | |
| SCHEMBL28453975 | 0.85 | MAOB (0.46) | MCL1ALDH1A1MAPTKDM4EKMT2A | |
| SCHEMBL28449039 | 0.83 | L3MBTL1 (0.51) | ALDH1A1MAPTKDM4EKMT2ALMNA | |
| SCHEMBL28452051 | 0.83 | MEN1 (0.59) | ALDH1A1MAPTKDM4EKMT2AHSD17B10 | |
| SCHEMBL28453044 | 0.83 | KDM4E (0.56) | AGTR1MCL1ALDH1A1MAPTKDM4E | |
| SCHEMBL13203082 | 0.82 | MEN1 (0.46) | ALDH1A1MAPTKDM4EKMT2ALMNA | |
| SCHEMBL13203040 | 0.82 | MEN1 (0.50) | AGTR1ALDH1A1MAPTKDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111499565-B | Preparation method of 2,3,4, 6-tetra-substituted pyridine compound | 台州学院 | 2022-04-26 | — | — | CN | disclosed |
| CN-111499565-A | Preparation method of 2,3,4, 6-tetra-substituted pyridine compound | 台州学院 | 2020-08-07 | — | — | CN | disclosed |