Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.56 |
| ▸ | MEN1 | O00255 | 6/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.51 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.51 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.51 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13203110 | 0.91 | MEN1 (0.52) | KDM4EMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL13203307 | 0.90 | MEN1 (0.50) | KDM4EMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL28026305 | 0.89 | MEN1 (0.53) | KDM4EMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL28446763 | 0.85 | ADORA1 (0.49) | KDM4EMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL29724212 | 0.85 | ADORA1 (0.49) | KDM4EMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL28446307 | 0.83 | AGTR1 (0.51) | KDM4EMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL28452051 | 0.83 | MEN1 (0.59) | KDM4EMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL28449039 | 0.83 | L3MBTL1 (0.51) | KDM4EMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL28457021 | 0.83 | ACACA (0.62) | KDM4EKMT2AALDH1A1MAPTHPGD | |
| SCHEMBL13203040 | 0.82 | MEN1 (0.50) | KDM4EMEN1KMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111499565-B | Preparation method of 2,3,4, 6-tetra-substituted pyridine compound | 台州学院 | 2022-04-26 | — | — | CN | disclosed |
| CN-111499565-A | Preparation method of 2,3,4, 6-tetra-substituted pyridine compound | 台州学院 | 2020-08-07 | — | — | CN | disclosed |