Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.55 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.55 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.55 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.55 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.52 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.52 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.52 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.52 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3035270 | 0.95 | TSHR (0.59) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL7386637 | 0.88 | ADRA2A (0.46) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL7385666 | 0.88 | ADRA2A (0.48) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL28435076 | 0.87 | ADORA3 (0.67) | ADRA1ATSHRALDH1A1HSD17B10KDM4E | |
| SCHEMBL7379815 | 0.87 | ADRA2A (0.45) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL7380762 | 0.87 | ADORA3 (0.51) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL11784686 | 0.85 | KMT2A (0.65) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL7267420 | 0.83 | CACNA1B (0.68) | ADORA3CACNA1B | |
| SCHEMBL7265410 | 0.82 | TSHR (0.65) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL28440531 | 0.81 | CACNA1B (0.44) | ADRA2AADRA2BADRA2CADRA1DADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111423362-A | Preparation method of two high-purity clevidipine butyrate impurities | 山东省药学科学院 | 2020-07-17 | — | — | CN | claimed |
| CN-111423362-A | Preparation method of two high-purity clevidipine butyrate impurities | 山东省药学科学院 | 2020-07-17 | — | — | CN | disclosed |