Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 2/20 | 0.42 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CCR1 | P32246 | 1/20 | 0.42 |
| ▸ | CCR5 | P51681 | 1/20 | 0.42 |
| ▸ | CCR8 | P51685 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4727994 | 0.90 | L3MBTL1 (0.65) | NPC1RAB9ASMN1; SMN2USP2ALOX15 | |
| SCHEMBL28261536 | 0.85 | SMN1; SMN2 (0.56) | NPC1RAB9ASMN1; SMN2USP2ALOX15 | |
| SCHEMBL24888335 | 0.84 | KDM4E (0.54) | NPC1RAB9ASMN1; SMN2USP2ALOX15 | |
| SCHEMBL4725082 | 0.81 | CYP1A2 (0.49) | USP2ALOX15TSHRHTTL3MBTL1 | |
| SCHEMBL29065472 | 0.80 | TYRO3 (0.42) | NPC1RAB9ASMN1; SMN2USP2ALOX15 | |
| SCHEMBL2955776 | 0.79 | LIPG (0.47) | USP2ALOX15TSHRHTTL3MBTL1 | |
| SCHEMBL21565078 | 0.79 | LIPG (0.47) | USP2ALOX15TSHRHTTL3MBTL1 | |
| SCHEMBL14678660 | 0.77 | KDM4E (0.46) | NPC1RAB9ASMN1; SMN2USP2ALOX15 | |
| SCHEMBL10358887 | 0.77 | KDM4E (0.46) | NPC1RAB9ASMN1; SMN2USP2ALOX15 | |
| SCHEMBL1130362 | 0.77 | KDM4E (0.46) | NPC1RAB9ASMN1; SMN2USP2ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109020877-B | Alkyl modified aryl pyridine compound and preparation method thereof | 同济大学 | 2020-08-18 | — | — | CN | disclosed |