Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 9/20 | 0.41 |
| ▸ | CTSD | P07339 | 1/20 | 0.39 |
| ▸ | GIPR | P48546 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 3/20 | 0.38 |
| ▸ | ACHE | P22303 | 3/20 | 0.38 |
| ▸ | GLP1R | P43220 | 2/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2844687 | 1.00 | GCGR (0.41) | GCGRCTSDGIPRALDH1A1GAA | |
| SCHEMBL2850248 | 0.84 | CTSD (0.38) | GCGRCTSDGIPRALDH1A1GAA | |
| SCHEMBL2847594 | 0.70 | SLC6A2 (0.38) | GCGRGIPRGLP1RPDK2 | |
| SCHEMBL24992155 | 0.70 | YTHDC1 (0.44) | ALDH1A1MEN1KMT2AYTHDC1 | |
| SCHEMBL8146212 | 0.69 | GAA (0.63) | ALDH1A1GAAGFERPDK2KDM4E | |
| SCHEMBL18341465 | 0.68 | YTHDC1 (0.44) | ALDH1A1GAAKDM4EMEN1KMT2A | |
| SCHEMBL21389913 | 0.68 | YTHDC1 (0.44) | ALDH1A1GAAKDM4EMEN1KMT2A | |
| SCHEMBL2652321 | 0.68 | GCGR (0.49) | GCGRGIPRALDH1A1GLP1RKDM4E | |
| SCHEMBL17139869 | 0.68 | YTHDC1 (0.46) | ALDH1A1KDM4EMEN1KMT2ANPSR1 | |
| SCHEMBL384806 | 0.68 | YTHDC1 (0.46) | ALDH1A1KDM4EMEN1KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010138901-A1 | CARBOXYLIC ACID-CONTAINING COMPOUNDS, DERIVATIVES THEREOF, AND RELATED METHODS OF USE | BIOGEN IDEC MA INC (US) | 2010-12-02 | — | — | WO | disclosed |