Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15661377 | 0.85 | TLR4 (0.33) | TLR4 | |
| SCHEMBL28617732 | 0.81 | — | — | |
| SCHEMBL31425655 | 0.73 | — | — | |
| SCHEMBL28061585 | 0.68 | TLR4 (0.50) | TLR4 | |
| SCHEMBL2521267 | 0.66 | — | — | |
| SCHEMBL1986436 | 0.66 | — | — | |
| SCHEMBL30665398 | 0.66 | ALDH1A1 (0.30) | ALDH1A1LMNATP53TSHR | |
| SCHEMBL7401293 | 0.66 | — | — | |
| SCHEMBL28077005 | 0.65 | MAPT (0.43) | TLR4 | |
| SCHEMBL29176239 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111647003-B | Triepoxyhexahydrochromone A, and pharmaceutical composition and application thereof | 中国科学院昆明植物研究所 | 2022-06-21 | — | — | CN | claimed |
| CN-111647003-A | Triepoxyhexahydrochromone A, pharmaceutical composition and application thereof | 中国科学院昆明植物研究所 | 2020-09-11 | — | — | CN | claimed |
| CN-111647003-B | Triepoxyhexahydrochromone A, and pharmaceutical composition and application thereof | 中国科学院昆明植物研究所 | 2022-06-21 | — | — | CN | disclosed |
| CN-111647003-A | Triepoxyhexahydrochromone A, pharmaceutical composition and application thereof | 中国科学院昆明植物研究所 | 2020-09-11 | — | — | CN | disclosed |