⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28635879 | 0.82 | — | — | |
| SCHEMBL30665398 | 0.81 | ALDH1A1 (0.30) | — | |
| SCHEMBL7220266 | 0.68 | ALDH1A1 (0.31) | — | |
| SCHEMBL28840778 | 0.67 | ALDH1A1 (0.30) | — | |
| SCHEMBL28447016 | 0.64 | TLR4 (0.33) | — | |
| SCHEMBL28617732 | 0.63 | — | — | |
| SCHEMBL8309556 | 0.63 | — | — | |
| SCHEMBL16770277 | 0.62 | — | — | |
| SCHEMBL31567960 | 0.60 | ALDH1A1 (0.30) | — | |
| SCHEMBL28992346 | 0.60 | ALDH1A1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118085015-A | Ring-merging compound as protein degradation agent and preparation method and application thereof | 江西济民可信集团有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-112457366-B | Parallel ring compound as protein degradation agent and preparation method and application thereof | 江西济民可信集团有限公司 | 2024-03-19 | — | — | CN | disclosed |