Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | CA9 | Q16790 | 3/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11922963 | 1.00 | ALDH1A1 (0.46) | ALDH1A1GRM3MAPK1LMNAMEN1 | |
| SCHEMBL14752965 | 0.89 | LMNA (0.51) | ALDH1A1LMNAHSD17B10SMN1; SMN2RIPK1 | |
| SCHEMBL14752961 | 0.89 | LMNA (0.51) | ALDH1A1LMNAHSD17B10SMN1; SMN2RIPK1 | |
| SCHEMBL14209040 | 0.89 | LMNA (0.51) | ALDH1A1LMNAHSD17B10SMN1; SMN2RIPK1 | |
| SCHEMBL11922853 | 0.84 | ALDH1A1 (0.55) | ALDH1A1MAPK1LMNAMEN1KMT2A | |
| SCHEMBL5517785 | 0.83 | ALDH1A1 (0.42) | ALDH1A1GRM3MAPK1LMNAMEN1 | |
| SCHEMBL12335980 | 0.81 | SMN1; SMN2 (0.44) | ALDH1A1GRM3MAPK1LMNAMEN1 | |
| SCHEMBL12788623 | 0.81 | ALDH1A1 (0.42) | ALDH1A1MAPK1LMNAMEN1KMT2A | |
| SCHEMBL14679331 | 0.81 | BCHE (0.47) | ALDH1A1MAPK1LMNAMEN1KMT2A | |
| SCHEMBL14752977 | 0.81 | POLB (0.41) | LMNAMEN1KMT2AMAPTRIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111601798-B | Bisamide sarcomere activating compounds and uses thereof | 美国安进公司 | 2023-08-11 | — | — | CN | disclosed |
| CN-111601798-A | Bisamide sarcomere activating compound and use thereof | 美国安进公司 | 2020-08-28 | — | — | CN | disclosed |