Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | SPR | P35270 | 4/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.34 |
| ▸ | TACR2 | P21452 | 3/20 | 0.34 |
| ▸ | CCR5 | P51681 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15229282 | 0.86 | ITGB1 (0.40) | MGLLNOTUMSLC6A3SLC6A2SLC6A4 | |
| SCHEMBL14676953 | 0.84 | DPP4 (0.47) | MGLLSLC6A3SLC6A2SLC6A4 | |
| SCHEMBL636430 | 0.78 | KDM4E (0.49) | — | |
| SCHEMBL969557 | 0.78 | KDM4E (0.49) | — | |
| SCHEMBL636431 | 0.78 | KDM4E (0.49) | — | |
| SCHEMBL4971090 | 0.77 | DPP4 (0.44) | SLC6A3 | |
| SCHEMBL4971082 | 0.77 | DPP4 (0.44) | SLC6A3 | |
| SCHEMBL15536002 | 0.74 | FPR2 (0.47) | MGLL | |
| SCHEMBL971535 | 0.73 | ALDH1A1 (0.44) | NOTUM | |
| SCHEMBL971537 | 0.73 | ALDH1A1 (0.44) | NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106349217-B | Serine/threonine kinase inhibitors | 阵列生物制药公司 | 2020-08-28 | — | — | CN | disclosed |