SCHEMBL2844749

SCHEMBL2844749

O=C(OCc1ccccc1)OCc1ccccc1O

nearest known ligand 0.57

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.57
ALDH1A1 P00352 4/20 0.52
MAPK1 P28482 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
LMNA P02545 1/20 0.50
SLC6A2 P23975 1/20 0.50
SLC6A3 Q01959 1/20 0.50
KMT2A Q03164 1/20 0.50
AKR1B1 P15121 1/20 0.50
IDO1 P14902 2/20 0.48
HCAR2 Q8TDS4 1/20 0.46
CA12 O43570 1/20 0.45
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
CA9 Q16790 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1011357 0.91 IDO1 (0.57) TDP1AKR1B1IDO1CA12CA2
SCHEMBL20097500 0.86 ALDH1A1 (0.52) TDP1ALDH1A1MAPK1L3MBTL1LMNA
SCHEMBL37382 0.84 ALDH1A1 (0.68) TDP1ALDH1A1MAPK1L3MBTL1LMNA
Bicarbonate SCHEMBL29183459 0.82 ALDH1A1 (0.65) TDP1ALDH1A1MAPK1L3MBTL1LMNA
Water SCHEMBL8217838 0.82 ALDH1A1 (0.65) TDP1ALDH1A1MAPK1L3MBTL1LMNA
Ammonia Solution, Strong SCHEMBL9998884 0.82 ALDH1A1 (0.65) TDP1ALDH1A1MAPK1L3MBTL1LMNA
SCHEMBL6589828 0.82 CA12 (0.50) ALDH1A1AKR1B1IDO1CA12CA1
SCHEMBL28662041 0.81 TDP1 (0.54) TDP1ALDH1A1MAPK1L3MBTL1LMNA
SCHEMBL1011358 0.81 AKR1B1 (0.57) TDP1AKR1B1IDO1CA12CA2
SCHEMBL6687005 0.81 ALDH1A1 (0.68) TDP1ALDH1A1MAPK1L3MBTL1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1724110-B1 Multilayered articles and method of manufacture thereof SABIC GLOBAL TECHNOLOGIES BV (NL) 2019-08-21 EP disclosed
EP-1971632-B1 METHOD OF PRODUCING POLYCARBONATE ARTICLES BY ROTATION MOLDING AND ROTATION MOLDED ARTICLES MADE BY THE METHOD SABIC GLOBAL TECHNOLOGIES BV (NL) 2017-01-11 EP disclosed
EP-1907465-B1 POLYCARBONATE COMPOSITIONS HAVING INFRARED ABSORBANCE, METHOD OF MANUFACTURE, AND ARTICLES PREPARED THEREFROM SABIC INNOVATIVE PLASTICS IP (NL) 2014-07-23 EP disclosed
EP-1529632-B1 Multilayered articles and method of manufacture thereof SABIC INNOVATIVE PLASTICS IP (NL) 2012-09-05 EP disclosed
EP-2202063-A2 Multilayered articles and method of manufacture thereof Sabic Innovative Plastics IP B.V. (NL) 2010-06-30 EP disclosed
EP-1559743-B1 Infra-red radiation absorption articles and method of manufacturing thereof SABIC INNOVATIVE PLASTICS IP (NL) 2009-02-18 EP disclosed
EP-1996650-A2 FLAME RETARDANT POLYCARBONATE COMPOSITIONS HAVING GOOD TRANSPARENCY AND LOW HAZE, METHOD OF MANUFACTURE, AND ARTICLES PREPARED THEREFROM Sabic Innovative Plastics IP B.V. (NL) 2008-12-03 EP disclosed
EP-1971632-A2 METHOD OF PRODUCING POLYCARBONATE ARTICLES BY ROTATION MOLDING AND ROTATION MOLDED ARTICLES MADE BY THE METHOD Sabic Innovative Plastics IP B.V. (NL) 2008-09-24 EP disclosed
EP-1907465-A2 POLYCARBONATE COMPOSITIONS HAVING INFRARED ABSORBANCE, METHOD OF MANUFACTURE, AND ARTICLES PREPARED THEREFROM General Electric Company (US) 2008-04-09 EP disclosed
WO-2008013579-A2 FLAME RETARDANT POLYCARBONATE COMPOSITIONS HAVING GOOD TRANSPARENCY AND LOW HAZE, METHOD OF MANUFACTURE, AND ARTICLES PREPARED THEREFROM SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2008-01-31 WO disclosed
US-20030120025-A1 Process for the production of polycarbonate GENERAL ELECTRIC COMPANY 2003-06-26 US disclosed
WO-2003050161-A1 PROCESS FOR PREPARING BRANCHED AROMATIC POLYCARBONATES GENERAL ELECTRIC COMPANY (US) 2003-06-19 WO disclosed
WO-2003022905-A1 PROCESS FOR THE PRODUCTION OF POLYCARBONATE GENERAL ELECTRIC COMPANY (US) 2003-03-20 WO disclosed
US-6525163-B1 Reducing static charge, improving heat aging, and lowering water absorption by increasing endcap levels GENERAL ELECTRIC COMPANY 2003-02-25 US disclosed
WO-2003010218-A1 METHOD OF POLYCARBONATE PREPARATION GENERAL ELECTRIC COMPANY (US) 2003-02-06 WO disclosed
US-20020132957-A1 Process for the production of polycarbonate GENERAL ELECTRIC COMPANY 2002-09-19 US disclosed
US-20020128425-A1 Process for the production of polycarbonate GENERAL ELECTRIC COMPANY 2002-09-12 US disclosed
US-6437083-B1 HAVING HIGH MELTING STRENGTHS IN A CONTINUOUS MELT REACTION SYSTEM; PHENOLIC BRANCHING AGENT GENERAL ELECTRIC COMPANY 2002-08-20 US disclosed
WO-2002060855-A2 PROCESS FOR THE PRODUCTION OF POLYCARBONATE GENERAL ELECTRIC COMPANY (US) 2002-08-08 WO disclosed
WO-2002060977-A1 PROCESS FOR THE PRODUCTION OF POLYCARBONATE GENERAL ELECTRIC COMPANY (US) 2002-08-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030120025-A1 Process for the production of polycarbonate RNGTT, CAPG, RPL30 TDP1 1918/4885ALDH1A1 2916/4885MAPK1 2887/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.