Formaldoxime

Formaldoxime

SCHEMBL28447516

C=NO.CN1CCCC1c1cc(Br)cnc1F

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CHRNB2 P17787 1/20 0.38
CHRNA4 P43681 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22686379 0.92 ALDH1A1 (0.42) CHRNB2CHRNA4
SCHEMBL22686378 0.92 ALDH1A1 (0.42) CHRNB2CHRNA4
SCHEMBL21647191 0.77 CHRNB2 (0.47) CHRNB2CHRNA4
SCHEMBL6366698 0.74 CHRNB2 (0.43) CHRNB2CHRNA4
SCHEMBL28961390 0.67 CHRNB2 (0.55) CHRNB2CHRNA4
SCHEMBL11233101 0.66 CHRNB2 (0.43) CHRNB2CHRNA4
SCHEMBL4299439 0.66 NTRK1 (0.47)
(+/-)Nicotine SCHEMBL27498265 0.66 ALDH1A1 (0.83) CHRNB2CHRNA4
SCHEMBL3058805 0.65 CHRNB2 (0.62) CHRNB2CHRNA4
SCHEMBL3058809 0.65 CHRNB2 (0.62) CHRNB2CHRNA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111620865-A Heterocyclic compound, application thereof and pharmaceutical composition containing same 苏州信诺维医药科技有限公司 2020-09-04 CN disclosed
CN-110156772-B Heterocyclic compound, application thereof and pharmaceutical composition containing same 苏州信诺维医药科技有限公司 2020-08-07 CN disclosed