Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | KCNA3 | P22001 | 2/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA3 | P07451 | 2/20 | 0.39 |
| ▸ | CA4 | P22748 | 2/20 | 0.39 |
| ▸ | CA6 | P23280 | 2/20 | 0.39 |
| ▸ | CA5A | P35218 | 2/20 | 0.39 |
| ▸ | CA7 | P43166 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28447632 | 0.92 | CA12 (0.49) | L3MBTL1POLBTHRBRECQLTDP1 | |
| SCHEMBL28451150 | 0.88 | LMNA (0.48) | L3MBTL1POLBTHRBRECQLTDP1 | |
| SCHEMBL28455364 | 0.85 | POLB (0.66) | L3MBTL1POLBTHRBRECQLTDP1 | |
| SCHEMBL29606551 | 0.85 | POLB (0.66) | L3MBTL1POLBTHRBRECQLTDP1 | |
| SCHEMBL28461022 | 0.82 | KMT2A (0.42) | KMT2AALOX15ALDH1A1 | |
| SCHEMBL28451133 | 0.77 | ALDH1A1 (0.46) | POLBKMT2ACA12CA1CA2 | |
| SCHEMBL28453632 | 0.77 | HPGD (0.58) | L3MBTL1POLBTHRBRECQLTDP1 | |
| SCHEMBL29606491 | 0.77 | HPGD (0.58) | L3MBTL1POLBTHRBRECQLTDP1 | |
| SCHEMBL28455092 | 0.77 | ALDH1A1 (0.40) | L3MBTL1RECQLKMT2AKCNA3ALOX15 | |
| SCHEMBL29606632 | 0.75 | HPGD (0.40) | L3MBTL1HPGDLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117285508-A | Preparation method of pyridyl pyrazole amide compound and intermediate thereof | 湖南化工研究院有限公司 | 2023-12-26 | — | — | CN | claimed |
| CN-114516855-A | Preparation of pyridylpyrazole amide compounds and intermediates therefor | 湖南化工研究院有限公司 | 2022-05-20 | — | — | CN | claimed |
| CN-114516854-A | Preparation method of 1-pyridyl pyrazole amide compound and intermediate thereof | 湖南化工研究院有限公司 | 2022-05-20 | — | — | CN | claimed |
| CN-111662269-B | 1-pyridyl pyrazole amide compound and preparation method and application thereof | 湖南化工研究院有限公司 | 2021-05-07 | — | — | CN | claimed |
| CN-111662269-A | 1-pyridyl pyrazole amide compound and preparation method and application thereof | 湖南化工研究院有限公司 | 2020-09-15 | — | — | CN | claimed |
| CN-117285508-A | Preparation method of pyridyl pyrazole amide compound and intermediate thereof | 湖南化工研究院有限公司 | 2023-12-26 | — | — | CN | disclosed |
| CN-114516855-A | Preparation of pyridylpyrazole amide compounds and intermediates therefor | 湖南化工研究院有限公司 | 2022-05-20 | — | — | CN | disclosed |
| CN-114516854-A | Preparation method of 1-pyridyl pyrazole amide compound and intermediate thereof | 湖南化工研究院有限公司 | 2022-05-20 | — | — | CN | disclosed |
| CN-111662269-B | 1-pyridyl pyrazole amide compound and preparation method and application thereof | 湖南化工研究院有限公司 | 2021-05-07 | — | — | CN | disclosed |
| CN-111662269-A | 1-pyridyl pyrazole amide compound and preparation method and application thereof | 湖南化工研究院有限公司 | 2020-09-15 | — | — | CN | disclosed |