Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRR1 | P24046 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ENPEP | Q07075 | 3/20 | 0.33 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.33 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.33 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.33 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.32 |
| ▸ | LCK | P06239 | 1/20 | 0.32 |
| ▸ | FYN | P06241 | 1/20 | 0.32 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.30 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.30 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL28384918 | 0.98 | GABRR1 (0.36) | GABRR1LMNAENPEPCACNA2D1CACNB3 | |
| Acetic Acid SCHEMBL5205545 | 0.98 | GABRR1 (0.36) | GABRR1LMNAENPEPCACNA2D1CACNB3 | |
| SCHEMBL606748 | 0.85 | ALDH1A1 (0.30) | — | |
| SCHEMBL539202 | 0.83 | — | — | |
| Succinic Acid SCHEMBL14342935 | 0.82 | LMNA (0.41) | GABRR1LMNAENPEPSLC1A3SLC1A2 | |
| Ammonia Solution, Strong SCHEMBL598220 | 0.80 | ALDH1A1 (0.30) | — | |
| Acetic Acid SCHEMBL3402077 | 0.80 | FFAR3 (0.44) | GABRR1LMNAENPEPCACNA2D1CACNB3 | |
| Acetic Acid SCHEMBL2392018 | 0.80 | FFAR3 (0.44) | GABRR1LMNAENPEPCACNA2D1CACNB3 | |
| Acetic Acid SCHEMBL1232731 | 0.78 | GABRR1 (0.42) | GABRR1LMNACACNA2D1CACNB3CACNA1C | |
| Acetic Acid SCHEMBL28422231 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111621773-B | Application of dithiocarbamate compounds in chemical palladium plating and chemical palladium plating composition | 广东东硕科技有限公司 | 2022-08-16 | — | — | CN | disclosed |
| CN-111621773-A | Application of dithiocarbamate compounds in chemical palladium plating and chemical palladium plating composition | 广东东硕科技有限公司 | 2020-09-04 | — | — | CN | disclosed |