Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | DNM1 | Q05193 | 6/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | ADH1B | P00325 | 1/20 | 0.32 |
| ▸ | ADH1C | P00326 | 1/20 | 0.32 |
| ▸ | ADH1A | P07327 | 1/20 | 0.32 |
| ▸ | ADH4 | P08319 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL4318746 | 1.00 | TSHR (0.40) | TSHRDNM1SMN1; SMN2LMNAALDH1A1 | |
| Bromide SCHEMBL28455801 | 1.00 | TSHR (0.40) | TSHRDNM1SMN1; SMN2LMNAALDH1A1 | |
| Hydrochloric Acid SCHEMBL28684543 | 0.96 | TSHR (0.40) | TSHRDNM1LMNAALDH1A1RAD52 | |
| Hydrochloric Acid SCHEMBL28835959 | 0.81 | TSHR (0.38) | TSHRDNM1LMNAALDH1A1RAD52 | |
| SCHEMBL27852636 | 0.81 | TSHR (0.32) | TSHR | |
| Bromide SCHEMBL9482055 | 0.81 | DNM1 (0.46) | TSHRDNM1SMN1; SMN2LMNAALDH1A1 | |
| Bromide SCHEMBL21494331 | 0.81 | DNM1 (0.46) | TSHRDNM1SMN1; SMN2LMNAALDH1A1 | |
| Bromide SCHEMBL29019024 | 0.81 | DNM1 (0.46) | TSHRDNM1SMN1; SMN2LMNAALDH1A1 | |
| Bromide SCHEMBL584403 | 0.81 | DNM1 (0.46) | TSHRDNM1SMN1; SMN2LMNAALDH1A1 | |
| Bromide SCHEMBL594635 | 0.81 | DNM1 (0.46) | TSHRDNM1SMN1; SMN2LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107245331-B | Oil displacement system and method for medium-permeability oil reservoir | 四川光亚聚合物化工有限公司 | 2020-08-11 | — | — | CN | disclosed |
| CN-106867497-B | Oil displacement system and method for low-permeability oil reservoir | 四川光亚聚合物化工有限公司 | 2020-05-22 | — | — | CN | disclosed |